SCHEMBL17508604

SCHEMBL17508604

CC(CC(O)CO)C(O)CCCO

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.39
PTPN1 P18031 1/20 0.38
LMNA P02545 3/20 0.33
CYP3A4 P08684 2/20 0.33
USP2 O75604 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
TRPV1 Q8NER1 1/20 0.33
TRPA1 O75762 1/20 0.33
ALDH1A1 P00352 1/20 0.33
TDP1 Q9NUW8 1/20 0.32
CYP2D6 P10635 2/20 0.31
SPHK1 Q9NYA1 1/20 0.31
GMNN O75496 1/20 0.31
POLB P06746 1/20 0.31
THPO P40225 1/20 0.31
MTOR P42345 1/20 0.31
BLM P54132 1/20 0.31
KDM4E B2RXH2 1/20 0.31
TP53 P04637 1/20 0.31
CYP1A2 P05177 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19492611 0.81 TRPV1 (0.39) THRBPTPN1LMNACYP3A4TRPV1
SCHEMBL9488939 0.79 THRB (0.43) THRBPTPN1LMNACYP3A4USP2
SCHEMBL15044044 0.79 LMNA (0.42) THRBLMNACYP3A4USP2SMN1; SMN2
SCHEMBL13737562 0.76 LMNA (0.44) THRBLMNACYP3A4USP2SMN1; SMN2
SCHEMBL6245826 0.76 TRPV1 (0.39) PTPN1LMNACYP3A4SMN1; SMN2TRPV1
SCHEMBL10584223 0.76 THRB (0.40) THRBPTPN1LMNACYP3A4USP2
SCHEMBL8596460 0.75 THRB (0.41) THRBPTPN1LMNACYP3A4USP2
SCHEMBL9064876 0.75 PTPN1 (0.33) THRBPTPN1CYP3A4USP2SMN1; SMN2
SCHEMBL16074684 0.75 LMNA (0.38) THRBLMNATRPA1ALDH1A1TDP1
SCHEMBL5702390 0.75 TRPV1 (0.42) THRBPTPN1LMNACYP3A4SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3180320-A1 PROCESS FOR PREPARING FURFURAL FROM BIOMASS SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. (NL) 2017-06-21 EP disclosed
WO-2016025678-A1 PROCESS FOR PREPARING FURFURAL FROM BIOMASS SHELL OIL COMPANY (US) 2016-02-18 WO disclosed