Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO2 | P16083 | 9/20 | 1.00 |
| ▸ | CYP19A1 | P11511 | 8/20 | 1.00 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | CASP1 | P29466 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | CASP7 | P55210 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | JAK2 | O60674 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17509824 | 0.83 | CYP19A1 (0.70) | NQO2CYP19A1MAPTKDM4EALDH1A1 | |
| SCHEMBL12559800 | 0.82 | NQO2 (0.70) | NQO2CYP19A1MAPTKDM4EALDH1A1 | |
| SCHEMBL17509826 | 0.80 | CYP19A1 (0.66) | NQO2CYP19A1MAPTKDM4EALDH1A1 | |
| SCHEMBL11217793 | 0.78 | MAPT (0.67) | NQO2CYP19A1MAPTKDM4EALDH1A1 | |
| SCHEMBL11503490 | 0.78 | NQO2 (0.64) | NQO2CYP19A1MAPTKDM4EALDH1A1 | |
| SCHEMBL20650932 | 0.78 | CYP19A1 (0.62) | NQO2CYP19A1MAPTKDM4EALDH1A1 | |
| SCHEMBL14438070 | 0.76 | CYP19A1 (0.61) | NQO2CYP19A1MAPTKDM4EALDH1A1 | |
| SCHEMBL21067704 | 0.76 | CYP19A1 (1.00) | NQO2CYP19A1MAPTKDM4EALDH1A1 | |
| SCHEMBL22271826 | 0.75 | CYP19A1 (0.60) | NQO2CYP19A1MAPTKDM4EALDH1A1 | |
| SCHEMBL14873828 | 0.75 | CYP19A1 (0.77) | NQO2CYP19A1MAPTKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160257651-A1 | NOVEL COMPOUND WITH ANTIBACTERIAL ACTIVITY | JUNTENDO EDUCATIONAL FOUNDATION (JP) | 2016-09-08 | — | — | US | disclosed |
| EP-2987787-A1 | NOVEL COMPOUND WITH ANTIBACTERIAL ACTIVITY | Juntendo Educational Foundation (JP) | 2016-02-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160257651-A1 | NOVEL COMPOUND WITH ANTIBACTERIAL ACTIVITY | SLC11A2, RELA, NFKBIA | NQO2 23/4885CYP19A1 3596/4885MAPT 3675/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.