Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 10/20 | 1.00 |
| ▸ | NQO2 | P16083 | 10/20 | 1.00 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17509827 | 0.76 | NQO2 (1.00) | CYP19A1NQO2MAPTL3MBTL1MEN1 | |
| SCHEMBL18347811 | 0.76 | CYP19A1 (0.75) | CYP19A1NQO2MAPTKDM4EALDH1A1 | |
| SCHEMBL6968661 | 0.73 | CYP19A1 (0.57) | CYP19A1NQO2MAPTMEN1POLB | |
| SCHEMBL18347791 | 0.71 | CYP19A1 (0.68) | CYP19A1NQO2MAPTALOX15KDM4E | |
| SCHEMBL14438070 | 0.71 | CYP19A1 (0.61) | CYP19A1NQO2MAPTL3MBTL1KDM4E | |
| SCHEMBL26555530 | 0.71 | CYP19A1 (0.55) | CYP19A1NQO2MAPTKDM4E | |
| SCHEMBL14873828 | 0.70 | CYP19A1 (0.77) | CYP19A1NQO2MAPTKDM4EALDH1A1 | |
| SCHEMBL1003108 | 0.68 | NQO2 (0.63) | CYP19A1NQO2KDM4EALDH1A1GLA | |
| SCHEMBL2633374 | 0.67 | PRMT1 (0.59) | CYP19A1NQO2MAPTL3MBTL1MEN1 | |
| SCHEMBL24854794 | 0.65 | MAPT (0.55) | CYP19A1NQO2MAPTL3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11446398-B2 | Regulated biocircuit systems | OBSIDIAN THERAPEUTICS, INC. (US) | 2022-09-20 | — | — | US | disclosed |
| US-20210254056-A1 | IDENTIFICATION AND TARGETED MODULATION OF GENE SIGNALING NETWORKS | CAMP4 THERAPEUTICS CORPORATION | 2021-08-19 | — | — | US | disclosed |
| US-20190192691-A1 | REGULATED BIOCIRCUIT SYSTEMS | OBSIDIAN THERAPEUTICS, INC. | 2019-06-27 | — | — | US | disclosed |