Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.62 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.57 |
| ▸ | MET | P08581 | 8/20 | 0.56 |
| ▸ | CA12 | O43570 | 3/20 | 0.56 |
| ▸ | CA4 | P22748 | 3/20 | 0.56 |
| ▸ | CA6 | P23280 | 3/20 | 0.56 |
| ▸ | CA5A | P35218 | 3/20 | 0.56 |
| ▸ | CA7 | P43166 | 3/20 | 0.56 |
| ▸ | CA9 | Q16790 | 3/20 | 0.56 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.56 |
| ▸ | CA5B | Q9Y2D0 | 3/20 | 0.56 |
| ▸ | TTR | P02766 | 1/20 | 0.54 |
| ▸ | HTR7 | P34969 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.54 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.54 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18060061 | 1.00 | MAOB (0.62) | MAOBEPHX2METCA12CA4 | |
| SCHEMBL31689164 | 1.00 | MAOB (0.62) | MAOBEPHX2METCA12CA4 | |
| SCHEMBL24140171 | 0.99 | MAOB (0.61) | MAOBEPHX2METCA12CA4 | |
| SCHEMBL3366430 | 0.89 | MAOB (0.60) | MAOBEPHX2METCA12CA4 | |
| SCHEMBL28390903 | 0.86 | PRKCA (0.68) | TTRHSD17B10ALOX5KDM4EMEN1 | |
| SCHEMBL6854015 | 0.85 | MAOB (0.62) | MAOBEPHX2METCA12CA4 | |
| SCHEMBL17938787 | 0.81 | PTPN1 (0.58) | EPHX2CA12CA9HSD17B10KDM1A | |
| SCHEMBL29531074 | 0.81 | LDHA (0.72) | MAOBEPHX2CA12CA9CA1 | |
| SCHEMBL27632141 | 0.81 | LDHA (0.72) | MAOBEPHX2CA12CA9CA1 | |
| SCHEMBL1029012 | 0.80 | GAA (0.56) | MAOBMETCA12CA4CA6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3539977-B1 | ENZYMES WITH CHLOROGENIC ACID ESTERASE ACTIVITY AND FERULOYL ESTERASE ACTIVITY | STERNENZYM GMBH & CO KG (DE) | 2022-03-23 | — | — | EP | disclosed |
| EP-3183263-B1 | ENZYMES WITH CHLOROGENIC ACID ESTERASE ACTIVITY AND FERULOYL ESTERASE ACTIVITY | STERNENZYM GMBH & CO KG (DE) | 2020-05-27 | — | — | EP | disclosed |
| EP-3539977-A1 | ENZYMES WITH CHLOROGENIC ACID ESTERASE ACTIVITY AND FERULOYL ESTERASE ACTIVITY | Stern Enzym GmbH & Co. KG (DE) | 2019-09-18 | — | — | EP | disclosed |
| EP-3183263-A1 | ENZYMES WITH CHLOROGENIC ACID ESTERASE ACTIVITY AND FERULOYL ESTERASE ACTIVITY | Stern Enzym GmbH & Co. KG (DE) | 2017-06-28 | — | — | EP | disclosed |
| WO-2016026793-A1 | ENZYMES WITH CHLOROGENIC ACID ESTERASE ACTIVITY AND FERULOYL ESTERASE ACTIVITY | STERN-ENZYM GMBH & CO. KG (DE) | 2016-02-25 | — | — | WO | disclosed |
| EP-2987802-A1 | An enzyme with chlorogenic acid esterase activity and feruloyl esterase activity | Stern Enzym GmbH & Co. KG (DE) | 2016-02-24 | — | — | EP | disclosed |