⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3392198 | 0.60 | — | — | |
| SCHEMBL28221053 | 0.57 | — | — | |
| SCHEMBL7631489 | 0.53 | — | — | |
| SCHEMBL9436725 | 0.50 | — | — | |
| SCHEMBL9925962 | 0.46 | — | — | |
| SCHEMBL13318485 | 0.43 | — | — | |
| Scyllitol SCHEMBL4447990 | 0.41 | LMNA (1.00) | — | |
| Scyllitol SCHEMBL959405 | 0.41 | LMNA (1.00) | — | |
| Scyllitol SCHEMBL188237 | 0.41 | LMNA (1.00) | — | |
| Scyllitol SCHEMBL12377889 | 0.41 | LMNA (1.00) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016029146-A1 | SPECIFIC INHIBITORS OF METHIONYL-TRNA SYNTHETASE | UNIVERSITY OF WASHINGTON (US) | 2016-02-25 | — | — | WO | claimed |
| WO-2023220428-A1 | COMPOSITIONS FOR EDITING ASS1 TRANSCRIPTS AND METHODS THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2023-11-16 | — | — | WO | disclosed |
| CN-115666652-A | Use of polyether compound | 千寿制药株式会社 | 2023-01-31 | — | — | CN | disclosed |
| CN-109535155-B | Apoptosis-inducing agents for the treatment of cancer and immune and autoimmune diseases | 艾伯维公司 | 2022-07-12 | — | — | CN | disclosed |
| CN-108137545-B | Triazole agonists of the APJ receptor | 美国安进公司 | 2020-09-22 | — | — | CN | disclosed |
| CN-107001375-A | The purposes of 6,7 dihydro-pyrazolos [1,5 a] pyrazine 4 (5H) assimilation compound and its negative sense allosteric modulators as MGLUR2 acceptors | 詹森药业有限公司 | 2017-08-01 | — | — | CN | disclosed |
| WO-2016172631-A2 | SUBSTRATE SELECTIVE INHIBITORS OF INSULIN-DEGRADING ENZYME (IDE) AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2016-10-27 | — | — | WO | disclosed |