Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | SNCA | P37840 | 1/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | RHOA | P61586 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28365597 | 0.93 | CYP3A4 (0.51) | CYP3A4ALDH1A1TSHRHSD17B10MAPT | |
| SCHEMBL20068188 | 0.91 | CYP3A4 (0.50) | CYP3A4ALDH1A1TSHRHSD17B10MAPT | |
| SCHEMBL16648508 | 0.86 | CYP3A4 (0.49) | CYP3A4ALDH1A1TSHRHSD17B10MAPT | |
| SCHEMBL4677464 | 0.85 | CYP3A4 (0.47) | CYP3A4ALDH1A1TSHRHSD17B10MAPT | |
| SCHEMBL6215267 | 0.85 | CYP3A4 (0.47) | CYP3A4ALDH1A1TSHRHSD17B10MAPT | |
| SCHEMBL28969438 | 0.81 | ALDH1A1 (0.46) | CYP3A4ALDH1A1TSHRMAPTHDAC4 | |
| Allyl 2-Furoate SCHEMBL1532489 | 0.78 | CYP3A4 (0.56) | CYP3A4ALDH1A1TSHRHSD17B10HPGD | |
| SCHEMBL30184248 | 0.77 | HDAC4 (0.46) | ALDH1A1TSHRHSD17B10MAPTHDAC4 | |
| SCHEMBL11497029 | 0.77 | ALDH1A1 (0.53) | CYP3A4ALDH1A1TSHRHSD17B10MAPT | |
| SCHEMBL175786 | 0.77 | SNCA (0.67) | CYP3A4ALDH1A1TSHRHSD17B10SNCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180066174-A1 | DRILLING FLUIDS CONTAINING POLYESTER POLYOLS | RESINATE MATERIALS GROUP, INC. | 2018-03-08 | — | — | US | claimed |
| WO-2016153866-A2 | DRILLING FLUIDS CONTAINING POLYESTER POLYOLS | RESINATE MATERIALS GROUP, INC. (US) | 2016-09-29 | — | — | WO | claimed |
| CN-111995753-B | Stimulus response membrane and preparation method thereof | 吉林大学 | 2021-06-18 | — | — | CN | disclosed |
| CN-111995753-A | Stimulus response membrane and preparation method thereof | 吉林大学 | 2020-11-27 | — | — | CN | disclosed |
| US-10662364-B2 | Drilling fluids containing polyester polyols | RESINATE MATERIALS GROUP, INC. (US) | 2020-05-26 | — | — | US | disclosed |
| CN-106893032-B | Aryl cyclobutene | 罗门哈斯电子材料有限责任公司 | 2020-03-31 | — | — | CN | disclosed |
| US-10030099-B2 | Digestion of keratin | RESINATE MATERIALS GROUP, INC. (US) | 2018-07-24 | — | — | US | disclosed |
| US-20180066174-A1 | DRILLING FLUIDS CONTAINING POLYESTER POLYOLS | RESINATE MATERIALS GROUP, INC. | 2018-03-08 | — | — | US | disclosed |
| EP-3184571-A1 | ARYLCYCLOBUTENES | Rohm and Haas Electronic Materials LLC (US) | 2017-06-28 | — | — | EP | disclosed |
| US-20170174805-A1 | ARYLCYCLOBUTENES | DOW GLOBAL TECHNOLOGIES LLC (US) | 2017-06-22 | — | — | US | disclosed |
| US-20170029551-A1 | DIGESTION OF KERATIN | RESINATE MATERIALS GROUP, INC. | 2017-02-02 | — | — | US | disclosed |
| WO-2016153866-A2 | DRILLING FLUIDS CONTAINING POLYESTER POLYOLS | RESINATE MATERIALS GROUP, INC. (US) | 2016-09-29 | — | — | WO | disclosed |
| WO-2016028841-A1 | DIGESTION OF KERATIN | RESINATE MATERIALS GROUP, INC. (US) | 2016-02-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10030099-B2 | Digestion of keratin | KRT18, UNG, PNMT | CYP3A4 501/4885ALDH1A1 473/4885TSHR 3865/4885 |
| US-20170029551-A1 | DIGESTION OF KERATIN | KRT18, UNG, PNMT | CYP3A4 501/4885ALDH1A1 473/4885TSHR 3865/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.