SCHEMBL17514596

SCHEMBL17514596

C#CCOc1[c]cccc1-c1ccc(Cl)c(F)c1

nearest known ligand 0.34

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
MAOB P27338 8/20 0.34
GSTP1 P09211 1/20 0.34
ALOX5AP P20292 3/20 0.33
FEN1 P39748 3/20 0.33
HTR7 P34969 1/20 0.32
CYP11B2 P19099 1/20 0.32
EGLN2 Q96KS0 1/20 0.32
MAOA P21397 5/20 0.31
KMO O15229 1/20 0.30
AR P10275 1/20 0.30
CNR1 P21554 1/20 0.30
EGFR P00533 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17514720 0.90 PTGS2 (0.38) MAOBGSTP1CYP11B2MAOACNR1
SCHEMBL17514986 0.81 GSTP1 (0.39) MAOBGSTP1MAOA
SCHEMBL17514688 0.81 MAOB (0.43) MAOBGSTP1MAOACNR1
SCHEMBL17514811 0.81 MAOB (0.34) MAOB
SCHEMBL17515002 0.81 MAOB (0.36) MAOBGSTP1MAOA
SCHEMBL17514927 0.81 MAOB (0.39) MAOBGSTP1MAOAEGFR
SCHEMBL17514944 0.80 MAOB (0.35) MAOBGSTP1MAOA
SCHEMBL17514964 0.80 MAOB (0.34) MAOBGSTP1
SCHEMBL17514786 0.80 HPGD (0.36) MAOBGSTP1EGFR
SCHEMBL17515031 0.80 MEN1 (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2016026830-A1 NOVEL FUNGICIDAL PYRAZOLE DERIVATIVES BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2016-02-25 WO disclosed