SCHEMBL17514944

SCHEMBL17514944

C#CCOc1[c]cccc1-c1cc(F)cc(F)c1

nearest known ligand 0.35

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
MAOB P27338 12/20 0.35
GSTP1 P09211 1/20 0.35
MAOA P21397 6/20 0.32
CYP1A1 P04798 1/20 0.31
CYP1A2 P05177 1/20 0.31
CYP1B1 Q16678 1/20 0.31
POLB P06746 1/20 0.30
MAPK1 P28482 1/20 0.30
HSD17B10 Q99714 1/20 0.30
ACHE P22303 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17514964 0.91 MAOB (0.34) MAOBGSTP1
SCHEMBL17515002 0.89 MAOB (0.36) MAOBGSTP1MAOACYP1A1CYP1A2
SCHEMBL17514986 0.87 GSTP1 (0.39) MAOBGSTP1MAOACYP1A1CYP1A2
SCHEMBL17514873 0.84 MAOB (0.33) MAOBGSTP1CYP1A1CYP1A2CYP1B1
SCHEMBL17514508 0.81 MAOB (0.35) MAOBGSTP1MAOACYP1A1CYP1A2
SCHEMBL17514623 0.81 MAOB (0.35) MAOBGSTP1MAOACYP1A1CYP1A2
SCHEMBL17514596 0.80 MAOB (0.34) MAOBGSTP1MAOA
SCHEMBL17514720 0.80 PTGS2 (0.38) MAOBGSTP1MAOA
SCHEMBL17514537 0.79 MAOB (0.35) MAOBGSTP1MAOACYP1A1CYP1A2
SCHEMBL17514482 0.79 MAOB (0.34) MAOBCYP1A1CYP1A2CYP1B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2016026830-A1 NOVEL FUNGICIDAL PYRAZOLE DERIVATIVES BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2016-02-25 WO disclosed