Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.46 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | GRM2 | Q14416 | 3/20 | 0.35 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.35 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | FASN | P49327 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19994059 | 0.98 | NISCH (0.45) | NISCHHSD11B1HTR1AHTR7HTR2A | |
| SCHEMBL17514566 | 0.91 | NISCH (0.49) | NISCHHSD11B1HTR1AHTR7HTR2A | |
| SCHEMBL436723 | 0.78 | MAOA (0.41) | KMT2AHPGDCYP19A1CYP11B1CYP11B2 | |
| SCHEMBL432638 | 0.78 | AHR (0.48) | HSD11B1HPGDNPC1RAB9AGAA | |
| SCHEMBL435253 | 0.77 | MAOA (0.42) | KMT2AHPGDCYP19A1CYP11B1CYP11B2 | |
| SCHEMBL434607 | 0.77 | AHR (0.47) | HSD11B1HPGDNPC1RAB9AGAA | |
| SCHEMBL435076 | 0.74 | ALDH1A1 (0.39) | KMT2AHPGDCYP19A1CYP11B1CYP11B2 | |
| SCHEMBL432355 | 0.74 | MAPT (0.49) | HSD11B1HPGDNPC1RAB9AGAA | |
| SCHEMBL31444456 | 0.73 | CHRNB4 (0.51) | NISCHHSD11B1HTR1AHTR7KMT2A | |
| SCHEMBL1262207 | 0.71 | GRM2 (0.48) | NISCHHSD11B1GRM2PDE3BPDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016026830-A1 | NOVEL FUNGICIDAL PYRAZOLE DERIVATIVES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2016-02-25 | — | — | WO | disclosed |