SCHEMBL17518451

SCHEMBL17518451

O=S(=O)(O)c1ccc(N=Nc2ccc(N=Nc3c(S(=O)(=O)O)cc4cc(Nc5ccccc5)ccc4c3O)cc2)c(S(=O)(=O)O)c1

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CD40 P25942 1/20 0.69
CD40LG P29965 1/20 0.69
ENPP2 Q13822 10/20 0.65
PRMT3 O60678 1/20 0.57
EP300 Q09472 1/20 0.57
PRMT6 Q96LA8 1/20 0.57
PRMT1 Q99873 1/20 0.57
MEN1 O00255 1/20 0.56
THRB P10828 1/20 0.56
KMT2A Q03164 1/20 0.56
TDP1 Q9NUW8 1/20 0.56
PHLPP2 Q6ZVD8 1/20 0.55
ALDH1A1 P00352 2/20 0.53
HIF1A Q16665 2/20 0.53
CYP1A2 P05177 1/20 0.53
SNCA P37840 1/20 0.50
NSD2 O96028 1/20 0.50
DUSP3 P51452 1/20 0.50
PTPN5 P54829 1/20 0.50
CASP7 P55210 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20735270 0.93 CD40 (0.64) CD40CD40LGENPP2PRMT3EP300
SCHEMBL20735312 0.93 CD40 (0.64) CD40CD40LGENPP2PRMT3EP300
SCHEMBL15386710 0.92 ENPP2 (0.65) CD40CD40LGENPP2PRMT3EP300
SCHEMBL17545808 0.92 ENPP2 (0.69) CD40CD40LGENPP2PRMT3EP300
SCHEMBL12757456 0.92 ENPP2 (0.69) CD40CD40LGENPP2PRMT3EP300
SCHEMBL13350540 0.92 ENPP2 (0.69) CD40CD40LGENPP2PRMT3EP300
SCHEMBL12757457 0.92 ENPP2 (0.70) CD40CD40LGENPP2PRMT3EP300
SCHEMBL19958240 0.92 ENPP2 (0.66) CD40CD40LGENPP2PRMT3EP300
SCHEMBL15386706 0.91 ENPP2 (0.66) CD40CD40LGENPP2PRMT3EP300
SCHEMBL19234940 0.91 CD40 (0.67) CD40CD40LGENPP2PRMT3EP300

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10209417-B2 Achromatic dye-based highly-transmissive polarization element, and polarization plate NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2019-02-19 US disclosed
US-20190048194-A1 Azo Compound Or Salt Thereof, And Polarizing Film Containing Same NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2019-02-14 US disclosed
US-20170153361-A1 Achromatic Polarizing Plate With High-Transmissivity And High-Degree Of Polarization NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2017-06-01 US disclosed
US-20160041321-A1 Achromatic Dye-Based Highly-Transmissive Polarization Element, And Polarization Plate NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2016-02-11 US disclosed