Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 7/20 | 0.69 |
| ▸ | OPRD1 | P41143 | 6/20 | 0.69 |
| ▸ | OPRK1 | P41145 | 6/20 | 0.69 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.54 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.54 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.54 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.53 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.52 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.52 |
| ▸ | KCNA3 | P22001 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL503892 | 0.87 | OPRM1 (0.73) | OPRM1OPRD1OPRK1ADRA1ASLC22A1 | |
| SCHEMBL8440281 | 0.86 | OPRM1 (0.71) | OPRM1OPRD1OPRK1ADRA1ASLC22A1 | |
| SCHEMBL8437630 | 0.84 | OPRM1 (0.69) | OPRM1OPRD1OPRK1ADRA1ASLC22A1 | |
| SCHEMBL476242 | 0.83 | OPRL1 (0.60) | OPRM1OPRD1OPRK1OPRL1MEN1 | |
| SCHEMBL12227090 | 0.82 | OPRM1 (0.61) | OPRM1OPRD1OPRK1ADRA1ASLC22A1 | |
| SCHEMBL11712071 | 0.82 | OPRM1 (1.00) | OPRM1OPRD1OPRK1ADRA1ASLC22A1 | |
| Hydrochloric Acid SCHEMBL2158958 | 0.82 | POLB (0.61) | OPRM1OPRD1OPRK1OPRL1MEN1 | |
| SCHEMBL8366154 | 0.82 | OPRL1 (0.56) | OPRM1OPRD1OPRK1ADRA1ASLC22A1 | |
| SCHEMBL6504241 | 0.81 | OPRM1 (0.65) | OPRM1OPRD1OPRK1ADRA1ASLC22A1 | |
| SCHEMBL7975314 | 0.79 | HSD11B1 (0.55) | OPRM1OPRD1OPRK1ADRA1AOPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9458160-B2 | Peripherally restricted diphenyl purine derivatives | RESEARCH TRIANGLE INSTITUTE (US) | 2016-10-04 | — | — | US | disclosed |
| US-20160046630-A1 | PERIPHERALLY RESTRICTED DIPHENYL PURINE DERIVATIVES | RES TRIANGLE INST (US) | 2016-02-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160046630-A1 | PERIPHERALLY RESTRICTED DIPHENYL PURINE DERIVATIVES | CNR1, CNR2, P2RY1 | OPRM1 33/4885OPRD1 34/4885OPRK1 22/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.