Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 6/20 | 0.56 |
| ▸ | PLA2G2A | P14555 | 6/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.56 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.56 |
| ▸ | TRPM8 | Q7Z2W7 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | HTR1D | P28221 | 2/20 | 0.48 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | MDH2 | P40926 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL17500243 | 0.99 | LTA4H (0.55) | LTA4HPLA2G2AMEN1KMT2AHSP90AA1 | |
| SCHEMBL20634174 | 0.91 | TRPM8 (0.57) | LTA4HPLA2G2AMEN1KMT2AHSP90AA1 | |
| SCHEMBL20634163 | 0.91 | TRPM8 (0.57) | LTA4HPLA2G2AMEN1KMT2AHSP90AA1 | |
| SCHEMBL20634172 | 0.91 | TRPM8 (0.57) | LTA4HPLA2G2AMEN1KMT2AHSP90AA1 | |
| Hydrochloric Acid SCHEMBL20610077 | 0.88 | LTA4H (0.62) | LTA4HPLA2G2AMEN1KMT2AHSP90AA1 | |
| Hydrochloric Acid SCHEMBL20610072 | 0.88 | LTA4H (0.62) | LTA4HPLA2G2AMEN1KMT2AHSP90AA1 | |
| Hydrochloric Acid SCHEMBL20610074 | 0.88 | LTA4H (0.62) | LTA4HPLA2G2AMEN1KMT2AHSP90AA1 | |
| SCHEMBL17500319 | 0.86 | LTA4H (0.50) | LTA4HPLA2G2AMEN1KMT2AHSP90AA1 | |
| Indorenate SCHEMBL10080621 | 0.84 | HTR2B (0.64) | MEN1KMT2ATRPM8KDM4EMAPT | |
| Indorenate SCHEMBL10566582 | 0.83 | HTR2B (0.63) | MEN1KMT2ATRPM8KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3177621-B1 | NOVEL HDAC6 INHIBITORS AND THEIR USES | UNIV REGENSBURG (DE) | 2021-11-10 | — | — | EP | disclosed |
| US-20170210743-A1 | NOVEL HDAC6 INHIBITORS AND THEIR USES | Universitätsklinikum Jena (DE) | 2017-07-27 | — | — | US | disclosed |
| US-20170210743-A1 | NOVEL HDAC6 INHIBITORS AND THEIR USES | Universitätsklinikum Jena (DE) | 2017-07-27 | — | — | US | disclosed |
| WO-2016020369-A1 | NOVEL HDAC6 INHIBITORS AND THEIR USES | UNIVERSITÄT REGENSBURG (DE) | 2016-02-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170210743-A1 | NOVEL HDAC6 INHIBITORS AND THEIR USES | HDAC6, HDAC5, HDAC4 | LTA4H 332/4885PLA2G2A 2883/4885MEN1 3320/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.