Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNP | P00491 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.58 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.58 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.56 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.55 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.55 |
| ▸ | PIM1 | P11309 | 1/20 | 0.52 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.52 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.52 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.52 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.52 |
| ▸ | POLA1 | P09884 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7199411 | 0.88 | PNP (0.62) | PNPLMNATP53HTTPDE4D | |
| SCHEMBL23647921 | 0.88 | PNP (0.62) | PNPLMNATP53HTTPDE4D | |
| SCHEMBL17521212 | 0.88 | PNP (0.62) | PNPLMNATP53HTTPDE4D | |
| SCHEMBL3707304 | 0.88 | PNP (0.62) | PNPLMNATP53HTTPDE4D | |
| SCHEMBL31685677 | 0.86 | PNP (0.55) | PNPLMNATP53HTTPDE4D | |
| SCHEMBL31685596 | 0.86 | PNP (0.55) | PNPLMNATP53HTTPDE4D | |
| SCHEMBL31685345 | 0.83 | HIF1A (0.62) | PNPLMNATP53HTTPDE4D | |
| SCHEMBL31685514 | 0.82 | PNP (0.62) | PNPLMNATP53HTTPDE4D | |
| SCHEMBL31685816 | 0.81 | PIM1 (0.55) | PNPLMNATP53HTTPDE4D | |
| SCHEMBL20165850 | 0.80 | PNP (0.64) | PNPLMNATP53HTTPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160039859-A1 | Novel NNA-DNA Adducts as Biomarkers for Detecting Exposure to Thirdhand Smoke | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2016-02-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160039859-A1 | Novel NNA-DNA Adducts as Biomarkers for Detecting Exposure to Thirdhand Smoke | OGG1, DNASE1L3, DDB1 | PNP 3530/4885LMNA 1833/4885TP53 833/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.