Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGF2R | P11717 | 4/20 | 0.56 |
| ▸ | CXCL10 | P02778 | 1/20 | 0.47 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.47 |
| ▸ | CCL2 | P13500 | 1/20 | 0.47 |
| ▸ | CCL5 | P13501 | 1/20 | 0.47 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.47 |
| ▸ | CD209 | Q9NNX6 | 2/20 | 0.41 |
| ▸ | LGALS3 | P17931 | 3/20 | 0.40 |
| ▸ | LGALS8 | O00214 | 2/20 | 0.40 |
| ▸ | LGALS4 | P56470 | 2/20 | 0.40 |
| ▸ | IFNG | P01579 | 1/20 | 0.35 |
| ▸ | FGF1 | P05230 | 1/20 | 0.35 |
| ▸ | FGF2 | P09038 | 1/20 | 0.35 |
| ▸ | BMP2 | P12643 | 1/20 | 0.35 |
| ▸ | VEGFA | P15692 | 1/20 | 0.35 |
| ▸ | SFRP1 | Q8N474 | 1/20 | 0.35 |
| ▸ | GJA1 | P17302 | 1/20 | 0.34 |
| ▸ | GJB2 | P29033 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17521920 | 0.93 | IGF2R (0.60) | IGF2RCXCL10CXCL8CCL2CCL5 | |
| SCHEMBL17521939 | 0.93 | IGF2R (0.57) | IGF2RCXCL10CXCL8CCL2CCL5 | |
| SCHEMBL17521929 | 0.93 | IGF2R (0.57) | IGF2RCXCL10CXCL8CCL2CCL5 | |
| SCHEMBL16126199 | 0.93 | IGF2R (0.57) | IGF2RCXCL10CXCL8CCL2CCL5 | |
| SCHEMBL17521901 | 0.87 | IGF2R (0.53) | IGF2RCXCL10CXCL8CCL2CCL5 | |
| SCHEMBL21083270 | 0.87 | IGF2R (0.65) | IGF2RCXCL10CXCL8CCL2CCL5 | |
| SCHEMBL21083292 | 0.87 | IGF2R (0.65) | IGF2RCXCL10CXCL8CCL2CCL5 | |
| SCHEMBL16126762 | 0.85 | IGF2R (0.44) | IGF2RCXCL10CXCL8CCL2CCL5 | |
| SCHEMBL17521951 | 0.85 | IGF2R (0.44) | IGF2RCXCL10CXCL8CCL2CCL5 | |
| SCHEMBL16126954 | 0.85 | IGF2R (0.67) | IGF2RCXCL10CXCL8CCL2CCL5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9919055-B2 | Sugar-linker-drug conjugates | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2018-03-20 | — | — | US | disclosed |
| US-20160045611-A1 | SUGAR-LINKER-DRUG CONJUGATES | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2016-02-18 | — | — | US | disclosed |
| US-20160045611-A1 | SUGAR-LINKER-DRUG CONJUGATES | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2016-02-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160045611-A1 | SUGAR-LINKER-DRUG CONJUGATES | FUT5, FUT6, B3GNT2 | IGF2R 1906/4885CXCL10 3377/4885CXCL8 3983/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.