Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.60 |
| ▸ | USP2 | O75604 | 3/20 | 0.60 |
| ▸ | ATM | Q13315 | 2/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.60 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.60 |
| ▸ | RGS12 | O14924 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.60 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.53 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.53 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.53 |
| ▸ | FLT4 | P35916 | 1/20 | 0.53 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29389679 | 0.95 | MEN1 (0.57) | MEN1KMT2AUSP2ATMMAPK1 | |
| SCHEMBL22164719 | 0.95 | MEN1 (0.57) | MEN1KMT2AUSP2ATMMAPK1 | |
| SCHEMBL15559791 | 0.95 | MEN1 (0.57) | MEN1KMT2AUSP2ATMMAPK1 | |
| SCHEMBL17525430 | 0.95 | MEN1 (0.57) | MEN1KMT2AUSP2ATMMAPK1 | |
| SCHEMBL17525431 | 0.95 | MEN1 (0.57) | MEN1KMT2AUSP2ATMMAPK1 | |
| SCHEMBL29387419 | 0.95 | MEN1 (0.57) | MEN1KMT2AUSP2ATMMAPK1 | |
| SCHEMBL28765285 | 0.95 | MEN1 (0.57) | MEN1KMT2AUSP2ATMMAPK1 | |
| Acetic Acid SCHEMBL29387147 | 0.91 | MEN1 (0.53) | MEN1KMT2AUSP2ATMMAPK1 | |
| SCHEMBL22181166 | 0.91 | MEN1 (0.58) | MEN1KMT2AUSP2ATMMAPK1 | |
| SCHEMBL17522979 | 0.86 | MEN1 (0.48) | MEN1KMT2AUSP2ATMMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160046584-A1 | COMPOSITIONS AND METHODS OF USING THE COMPOSITIONS FOR PLAQUE SOFTENING | ALUMEND, LLC (US) | 2016-02-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160046584-A1 | COMPOSITIONS AND METHODS OF USING THE COMPOSITIONS FOR PLAQUE SOFTENING | APOB, PLG, LIPG | MEN1 2681/4885KMT2A 3857/4885USP2 2842/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.