Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17523765 | 1.00 | SIGMAR1 (0.37) | SIGMAR1KCNH2 | |
| SCHEMBL15383401 | 1.00 | SIGMAR1 (0.37) | SIGMAR1KCNH2 | |
| SCHEMBL21015388 | 1.00 | SIGMAR1 (0.37) | SIGMAR1KCNH2 | |
| SCHEMBL15183494 | 0.98 | SIGMAR1 (0.38) | SIGMAR1 | |
| SCHEMBL15183480 | 0.91 | CACNA2D1 (0.32) | SIGMAR1 | |
| SCHEMBL17523776 | 0.89 | SIGMAR1 (0.44) | SIGMAR1KCNH2 | |
| SCHEMBL14731785 | 0.89 | SIGMAR1 (0.44) | SIGMAR1KCNH2 | |
| SCHEMBL21016075 | 0.89 | SIGMAR1 (0.44) | SIGMAR1KCNH2 | |
| SCHEMBL17523762 | 0.89 | SIGMAR1 (0.44) | SIGMAR1KCNH2 | |
| SCHEMBL8361776 | 0.86 | SIGMAR1 (0.46) | SIGMAR1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160039879-A1 | NOVEL CYCLOSPORIN DERIVATIVES AND USES THEREOF | S&T GLOBAL INC. (US) | 2016-02-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160039879-A1 | NOVEL CYCLOSPORIN DERIVATIVES AND USES THEREOF | FKBP1B, MALT1, FKBP5 | SIGMAR1 3999/4885KCNH2 3628/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.