Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 1/20 | 0.38 |
| ▸ | ACACA | Q13085 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.31 |
| ▸ | BCL2 | P10415 | 1/20 | 0.31 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17523798 | 1.00 | ACACB (0.38) | ACACBACACAALDH1A1TSHRHTR2A | |
| SCHEMBL17523851 | 0.94 | ACACB (0.41) | ACACBACACAALDH1A1TSHRHTR2A | |
| SCHEMBL17523849 | 0.94 | ACACB (0.41) | ACACBACACAALDH1A1TSHRHTR2A | |
| SCHEMBL17523927 | 0.92 | ACACB (0.44) | ACACBACACAALDH1A1TSHRDNM1 | |
| SCHEMBL17523928 | 0.92 | ACACB (0.44) | ACACBACACAALDH1A1TSHRDNM1 | |
| SCHEMBL9671940 | 0.89 | ALDH1A1 (0.45) | ACACBACACAALDH1A1TSHRHTR2A | |
| SCHEMBL2454527 | 0.86 | ALDH1A1 (0.47) | ALDH1A1TSHRHTR2AHRH1DNM1 | |
| SCHEMBL14293914 | 0.83 | ACACB (0.48) | ACACBACACAALDH1A1TSHRRIPK1 | |
| SCHEMBL17523800 | 0.79 | ACACB (0.36) | ACACBACACALMNARIPK1 | |
| SCHEMBL17523801 | 0.79 | ACACB (0.36) | ACACBACACALMNARIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160039879-A1 | NOVEL CYCLOSPORIN DERIVATIVES AND USES THEREOF | S&T GLOBAL INC. (US) | 2016-02-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160039879-A1 | NOVEL CYCLOSPORIN DERIVATIVES AND USES THEREOF | FKBP1B, MALT1, FKBP5 | ACACB 1771/4885ACACA 2462/4885ALDH1A1 2376/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.