Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 1/20 | 0.42 |
| ▸ | ACACA | Q13085 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.35 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | GPR84 | Q9NQS5 | 5/20 | 0.33 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.31 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.31 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.31 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17523929 | 1.00 | ACACB (0.42) | ACACBACACASIGMAR1L3MBTL1PLA2G1B | |
| SCHEMBL17523852 | 0.98 | SIGMAR1 (0.42) | ACACBACACASIGMAR1L3MBTL1PLA2G1B | |
| SCHEMBL17523853 | 0.98 | SIGMAR1 (0.42) | ACACBACACASIGMAR1L3MBTL1PLA2G1B | |
| SCHEMBL17523801 | 0.92 | ACACB (0.36) | ACACBACACASIGMAR1L3MBTL1RIPK1 | |
| SCHEMBL17523800 | 0.92 | ACACB (0.36) | ACACBACACASIGMAR1L3MBTL1RIPK1 | |
| SCHEMBL1147629 | 0.86 | SIGMAR1 (0.50) | ACACBACACASIGMAR1L3MBTL1PLA2G1B | |
| SCHEMBL17526514 | 0.82 | PLA2G1B (0.47) | SIGMAR1L3MBTL1PLA2G1BPLA2G2AFFAR4 | |
| SCHEMBL17526657 | 0.82 | PLA2G1B (0.47) | SIGMAR1L3MBTL1PLA2G1BPLA2G2AFFAR4 | |
| SCHEMBL21016075 | 0.82 | SIGMAR1 (0.44) | SIGMAR1PAOXSLC6A4KCNH2CACNA2D1 | |
| SCHEMBL17523776 | 0.82 | SIGMAR1 (0.44) | SIGMAR1PAOXSLC6A4KCNH2CACNA2D1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160039879-A1 | NOVEL CYCLOSPORIN DERIVATIVES AND USES THEREOF | S&T GLOBAL INC. (US) | 2016-02-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160039879-A1 | NOVEL CYCLOSPORIN DERIVATIVES AND USES THEREOF | FKBP1B, MALT1, FKBP5 | ACACB 1771/4885ACACA 2462/4885SIGMAR1 3999/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.