Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR4 | P61073 | 2/20 | 0.44 |
| ▸ | GNAO1 | P09471 | 5/20 | 0.39 |
| ▸ | GNAI3 | P08754 | 4/20 | 0.38 |
| ▸ | GNAI1 | P63096 | 4/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.34 |
| ▸ | SOD3 | P08294 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17524190 | 1.00 | CXCR4 (0.44) | CXCR4GNAO1GNAI3GNAI1CHRM2 | |
| SCHEMBL17524115 | 0.98 | CXCR4 (0.41) | CXCR4GNAO1GNAI3GNAI1CHRM2 | |
| SCHEMBL17524116 | 0.98 | CXCR4 (0.41) | CXCR4GNAO1GNAI3GNAI1CHRM2 | |
| SCHEMBL17524042 | 0.94 | CXCR4 (0.40) | CXCR4GNAO1GNAI3GNAI1CHRM2 | |
| SCHEMBL17524044 | 0.94 | CXCR4 (0.40) | CXCR4GNAO1GNAI3GNAI1CHRM2 | |
| SCHEMBL17523966 | 0.87 | CXCR4 (0.42) | CXCR4GNAO1GNAI3GNAI1CHRM2 | |
| SCHEMBL17523965 | 0.87 | CXCR4 (0.42) | CXCR4GNAO1GNAI3GNAI1CHRM2 | |
| SCHEMBL17524194 | 0.86 | PAOX (0.39) | GNAO1GNAI3GNAI1CHRM2CHRM4 | |
| SCHEMBL17524195 | 0.86 | GNAO1 (0.34) | GNAO1GNAI3GNAI1ALDH1A1KDM4E | |
| SCHEMBL17524196 | 0.86 | GNAO1 (0.34) | GNAO1GNAI3GNAI1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160039879-A1 | NOVEL CYCLOSPORIN DERIVATIVES AND USES THEREOF | S&T GLOBAL INC. (US) | 2016-02-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160039879-A1 | NOVEL CYCLOSPORIN DERIVATIVES AND USES THEREOF | FKBP1B, MALT1, FKBP5 | CXCR4 2243/4885GNAO1 4461/4885GNAI3 2852/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.