Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKACA | P17612 | 1/20 | 0.39 |
| ▸ | PRKACG | P22612 | 1/20 | 0.39 |
| ▸ | PRKACB | P22694 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
| ▸ | ATR | Q13535 | 1/20 | 0.34 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.33 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.32 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.31 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18387 | 0.81 | CSNK1D (0.43) | PRKACAPRKACGPRKACBCTSKACVR1 | |
| SCHEMBL280628 | 0.81 | CSNK1D (0.43) | PRKACAPRKACGPRKACBCTSKACVR1 | |
| SCHEMBL8321907 | 0.81 | CSNK1D (0.43) | PRKACAPRKACGPRKACBCTSKACVR1 | |
| SCHEMBL24540923 | 0.80 | KMT2A (0.40) | PRKACAPRKACGPRKACBCTSKATR | |
| Hydrochloric Acid SCHEMBL28214300 | 0.79 | CSNK1D (0.43) | PRKACAPRKACGPRKACBCTSKACVR1 | |
| Hydrochloric Acid SCHEMBL28500586 | 0.79 | CSNK1D (0.43) | PRKACAPRKACGPRKACBCTSKACVR1 | |
| SCHEMBL3399522 | 0.77 | PRKACA (0.47) | PRKACAPRKACGPRKACBCTSKATR | |
| SCHEMBL21717791 | 0.77 | MAPT (0.44) | PRKACAPRKACGPRKACBCTSKATR | |
| SCHEMBL22589151 | 0.77 | CHRNA7 (0.47) | PRKACAPRKACGPRKACBCTSK | |
| SCHEMBL2944138 | 0.77 | CHRNA7 (0.47) | PRKACAPRKACGPRKACBCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016020295-A1 | OPTIONALLY FUSED HETEROCYCLYL-SUBSTITUTED DERIVATIVES OF PYRIMIDINE USEFUL FOR THE TREATMENT OF INFLAMMATORY, METABOLIC, ONCOLOGIC AND AUTOIMMUNE DISEASES | NUEVOLUTION A/S (DK) | 2016-02-11 | — | — | WO | disclosed |