Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | CTSK | P43235 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.35 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11947774 | 1.00 | BTK (0.44) | BTKGAACTSKKMT2AMEN1 | |
| SCHEMBL617190 | 0.91 | BTK (0.49) | BTKGAACTSKKMT2AMEN1 | |
| SCHEMBL1694399 | 0.90 | GAA (0.45) | BTKGAACTSKKMT2AMEN1 | |
| SCHEMBL20583619 | 0.86 | BTK (0.45) | BTKGAACTSKKMT2AMEN1 | |
| SCHEMBL1062209 | 0.85 | BTK (0.51) | BTKGAACTSKKMT2AKDM1A | |
| SCHEMBL20960871 | 0.85 | BTK (0.51) | BTKGAACTSKKMT2AKDM1A | |
| SCHEMBL20331988 | 0.85 | BTK (0.51) | BTKGAACTSKKMT2AKDM1A | |
| SCHEMBL14853197 | 0.84 | GAA (0.48) | BTKGAACTSKKMT2AMEN1 | |
| SCHEMBL27935380 | 0.82 | CTSK (0.41) | BTKGAACTSKKMT2AKDM1A | |
| SCHEMBL23782217 | 0.81 | BTK (0.39) | BTKGAACTSKKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016021192-A1 | PROCESS FOR PRODUCTION OF (S)-(TETRAHYDROFURAN-3-YL)HYDRAZINE | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2016-02-11 | — | — | WO | disclosed |