Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB4 | P30926 | 4/20 | 0.36 |
| ▸ | CHRNA3 | P32297 | 4/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.36 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20175322 | 0.89 | CHRNB4 (0.41) | CHRNB4CHRNA3PIK3CDPIK3CAPIK3CB | |
| SCHEMBL17505047 | 0.82 | HTT (0.40) | CHRNB4CHRNA3PIK3CDPIK3CAPIK3CB | |
| SCHEMBL5519155 | 0.82 | GAA (0.47) | CHRNB4CHRNA3PIK3CDPIK3CAPIK3CB | |
| SCHEMBL20175319 | 0.80 | GAA (0.43) | CHRNB4CHRNA3PIK3CDPIK3CAPIK3CB | |
| SCHEMBL19602142 | 0.80 | HTT (0.38) | ALDH1A1HTTKDM4ELMNAGAA | |
| SCHEMBL17505042 | 0.80 | ALDH1A1 (0.42) | CHRNB4CHRNA3ALDH1A1KDM4ELMNA | |
| SCHEMBL5518656 | 0.80 | ALDH1A1 (0.42) | CHRNB4CHRNA3PIK3CDPIK3CAPIK3CB | |
| SCHEMBL499016 | 0.79 | NOS3 (0.48) | CHRNB4CHRNA3PIK3CDPIK3CAPIK3CB | |
| SCHEMBL17505044 | 0.78 | ALDH1A1 (0.50) | ALDH1A1HTTLMNAGAAKMT2A | |
| SCHEMBL20175320 | 0.78 | ALDH1A1 (0.41) | CHRNB4CHRNA3ALDH1A1KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016020490-A1 | BENZOXAZINE DERIVATIVES AND USE IN HAIR DYEING | L'OREAL (FR) | 2016-02-11 | — | — | WO | disclosed |