Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 4/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA7 | P43166 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | VCP | P55072 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | TACR1 | P25103 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2304714 | 1.00 | TSHR (0.48) | TSHRTRPA1CA1CA2CA7 | |
| SCHEMBL3813606 | 0.85 | TRPA1 (0.48) | TSHRTRPA1KMT2AALDH1A1HTT | |
| SCHEMBL647500 | 0.85 | TRPA1 (0.48) | TSHRTRPA1KMT2AALDH1A1HTT | |
| SCHEMBL647501 | 0.85 | TRPA1 (0.48) | TSHRTRPA1KMT2AALDH1A1HTT | |
| SCHEMBL3510081 | 0.84 | TSHR (0.47) | TSHRTRPA1CA1CA2CA7 | |
| SCHEMBL24004136 | 0.84 | TSHR (0.50) | TSHRTRPA1CA1CA2CA7 | |
| SCHEMBL27129558 | 0.83 | TSHR (0.45) | TSHRTRPA1CA1CA2CA7 | |
| SCHEMBL27032236 | 0.83 | TSHR (0.45) | TSHRTRPA1CA1CA2CA7 | |
| SCHEMBL27032017 | 0.83 | TSHR (0.45) | TSHRTRPA1CA1CA2CA7 | |
| SCHEMBL13641899 | 0.81 | TSHR (0.56) | TSHRCA1CA2CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016025363-A1 | BRYOSTATIN ANALOGS AND USE THEREOF AS ANTIVIRAL AGENTS | UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) | 2016-02-18 | — | — | WO | disclosed |