Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 4/20 | 0.44 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.44 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.44 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | AGXT | P21549 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL647501 | 1.00 | TRPA1 (0.48) | TRPA1TSHRSLC1A3SLC1A2SLC1A1 | |
| SCHEMBL3813606 | 1.00 | TRPA1 (0.48) | TRPA1TSHRSLC1A3SLC1A2SLC1A1 | |
| SCHEMBL2781956 | 0.93 | MAPT (0.43) | TRPA1TSHRSLC1A3SLC1A2SLC1A1 | |
| SCHEMBL23423410 | 0.93 | MAPT (0.43) | TRPA1TSHRSLC1A3SLC1A2SLC1A1 | |
| SCHEMBL872642 | 0.93 | MAPT (0.43) | TRPA1TSHRSLC1A3SLC1A2SLC1A1 | |
| SCHEMBL27133457 | 0.89 | TRPA1 (0.41) | TRPA1TSHRSLC1A3SLC1A2SLC1A1 | |
| SCHEMBL27032735 | 0.89 | TRPA1 (0.41) | TRPA1TSHRSLC1A3SLC1A2SLC1A1 | |
| SCHEMBL2304714 | 0.85 | TSHR (0.48) | TRPA1TSHRKMT2AMAPTALDH1A1 | |
| SCHEMBL17525899 | 0.85 | TSHR (0.48) | TRPA1TSHRKMT2AMAPTALDH1A1 | |
| SCHEMBL27902244 | 0.85 | TRPA1 (0.50) | TRPA1TSHRSLC1A3SLC1A2SLC1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 104 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260144795-A1 | SPIROMACROCYCLIC OREXIN 2 RECEPTOR AGONISTS | H. LUNDBECK A/S (DK) | 2026-05-28 | — | — | US | disclosed |
| US-20260137706-A1 | METHODS OF TREATING INFLAMMATORY DISEASES | INTERLINE THERAPEUTICS INC (US) | 2026-05-21 | — | — | US | disclosed |
| EP-4724440-A1 | METHODS OF TREATING INFLAMMATORY DISEASES | Interline Therapeutics, Inc. (US) | 2026-04-15 | — | — | EP | disclosed |
| US-20260098039-A1 | SOLID FORMS OF COMPOUND I OR SALTS THEREOF | JACOBIO PHARMACEUTICALS CO., LTD. (CN) | 2026-04-09 | — | — | US | disclosed |
| EP-4652164-A1 | INHIBITORS OF CYCLIC GMP-AMP SYNTHASE AND USES THEREOF | Ventus Therapeutics U.S., Inc. (US) | 2025-11-26 | — | — | EP | disclosed |
| EP-4611820-A1 | EXATECAN DERIVATIVES AND ANTIBODY-DRUG CONJUGATES THEREOF | ALX Oncology Inc. (US) | 2025-09-10 | — | — | EP | disclosed |
| CN-120118087-A | Preparation and application of PARP7 inhibitor | 药雅科技(上海)有限公司 | 2025-06-10 | — | — | CN | disclosed |
| CN-119731176-A | Solid forms of Compound I or salts thereof | 北京加科思新药研发有限公司 | 2025-03-28 | — | — | CN | disclosed |
| US-20250034120-A1 | PYRIDAZINONES AS PARP7 INHIBITORS | RIBON THERAPEUTICS, INC. | 2025-01-30 | — | — | US | disclosed |
| WO-2024254539-A1 | METHODS OF TREATING INFLAMMATORY DISEASES | INTERLINE THERAPEUTICS, INC. (US) | 2024-12-12 | — | — | WO | disclosed |
| US-4642373-A | Substituted dodecahydrotripheylenes, and decahydropyrrolo[1,2-f]phenanthridines as CNS agents | PFIZER INC. (US) | 1987-02-10 | — | — | US | disclosed |
| EP-0090526-B1 | SUBSTITUTED DODECAHYDROTRIPHENYLENES, DECAHYDRO-1H-CYCLOPENTA(1)PHENANTHRENES, DECAHYDRO-1H-PYRIDO(1,2-F)PHENANTHRIDINES AND DECAHYDROPYRROLO(1,2-F)PHENANTHRIDINES AS CNS AGENTS | PFIZER INC. (US) | 1986-11-26 | — | — | EP | disclosed |
| US-4576964-A | ANALGESICS, ANTIEMETICS | PFIZER INC. (US) | 1986-03-18 | — | — | US | disclosed |
| EP-0079134-B1 | STEREOSPECIFIC SYNTHESIS OF 5-PHENYL-2S-PENTANOL | PFIZER INC. (US) | 1985-02-06 | — | — | EP | disclosed |
| US-4476131-A | ANTIEMETICS, ANALGESICS | PFIZER INC. (US) | 1984-10-09 | — | — | US | disclosed |
| US-4473704-A | ANALGESICS, ANTIEMETICS | PFIZER INC. (US) | 1984-09-25 | — | — | US | disclosed |
| US-4412958-A | Stereospecific synthesis of 5-phenyl-2S-pentanol | PFIZER INC. (US) | 1983-11-01 | — | — | US | disclosed |
| EP-0090526-A1 | Substituted dodecahydrotriphenylenes, decahydro-1H-cyclopenta(1)phenanthrenes, decahydro-1H-pyrido(1,2-f)phenanthridines and decahydropyrrolo(1,2-f)phenanthridines as CNS agents | PFIZER INC. (US) | 1983-10-05 | — | — | EP | disclosed |
| EP-0090516-A1 | Substituted hexahydropyrrolo(1,2-a)-quinoline, hexahydro-1H-pyrido(1,2-a)-quinoline, hexahydrobenzo(3)indene and octahydrophenanthrene CNS agents | PFIZER INC. (US) | 1983-10-05 | — | — | EP | disclosed |
| EP-0079134-A1 | Stereospecific synthesis of 5-phenyl-2S-pentanol | PFIZER INC. (US) | 1983-05-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260144795-A1 | SPIROMACROCYCLIC OREXIN 2 RECEPTOR AGONISTS | HCRTR2, HCRTR1, CRHR1 | TRPA1 516/4885TSHR 119/4885SLC1A3 1051/4885 |
| US-20250034120-A1 | PYRIDAZINONES AS PARP7 INHIBITORS | PARP2, PARP1, PARP4 | TRPA1 4407/4885TSHR 3587/4885SLC1A3 4627/4885 |
| US-20260137706-A1 | METHODS OF TREATING INFLAMMATORY DISEASES | NR3C1, CCR1, CXCR2 | TRPA1 2630/4885TSHR 1291/4885SLC1A3 3048/4885 |
| US-20260098039-A1 | SOLID FORMS OF COMPOUND I OR SALTS THEREOF | LDHA, SLC25A11, LDHB | TRPA1 1405/4885TSHR 2751/4885SLC1A3 764/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.