Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CBFB | Q13951 | 7/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 7/20 | 0.36 |
| ▸ | MGAM | O43451 | 6/20 | 0.36 |
| ▸ | SI | P14410 | 6/20 | 0.36 |
| ▸ | MGAM2 | Q2M2H8 | 6/20 | 0.36 |
| ▸ | DHODH | Q02127 | 3/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | RUNX1 | Q01196 | 1/20 | 0.33 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17525999 | 0.84 | CBFB (0.40) | CBFBALDH1A1TP53CYP3A4CYP2D6 | |
| SCHEMBL17525998 | 0.79 | BTK (0.44) | CBFBALDH1A1TP53CYP3A4CYP2D6 | |
| SCHEMBL179154 | 0.72 | CBFB (0.72) | CBFBALDH1A1TP53CYP3A4CYP2D6 | |
| SCHEMBL179161 | 0.70 | NPC1 (0.52) | CBFBALDH1A1TP53HPGDCYP2C19 | |
| SCHEMBL17525993 | 0.68 | CBFB (0.51) | CBFBALDH1A1TP53CYP3A4CYP2D6 | |
| SCHEMBL19230477 | 0.66 | CBFB (0.47) | CBFBGAAMGAMSIMGAM2 | |
| SCHEMBL18764094 | 0.63 | CBFB (0.44) | CBFBALDH1A1TP53CYP3A4CYP2D6 | |
| SCHEMBL124235 | 0.62 | CBFB (0.68) | CBFBALDH1A1TP53CYP3A4CYP2D6 | |
| SCHEMBL2578465 | 0.61 | CBFB (0.73) | CBFBGAAMGAMSIMGAM2 | |
| SCHEMBL125170 | 0.60 | CBFB (0.52) | CBFBALDH1A1TP53HPGDALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016025744-A1 | CANCER THERAPEUTICS | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) | 2016-02-18 | — | — | WO | disclosed |