Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 8/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.41 |
| ▸ | HRH1 | P35367 | 2/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.41 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | HTR7 | P34969 | 1/20 | 0.40 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17526207 | 0.89 | HRH3 (0.46) | SIGMAR1HRH3SLC6A2HRH1CHRM2 | |
| SCHEMBL17526209 | 0.88 | SIGMAR1 (0.42) | SIGMAR1HRH3SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL20332809 | 0.87 | SIGMAR1 (0.43) | SIGMAR1HRH3 | |
| SCHEMBL17528490 | 0.86 | SIGMAR1 (0.41) | SIGMAR1HRH3SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL17528473 | 0.86 | KDM4E (0.43) | SIGMAR1HRH3SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL31249827 | 0.86 | LTA4H (0.43) | SIGMAR1HRH3SLC6A4 | |
| SCHEMBL20332923 | 0.86 | SIGMAR1 (0.43) | SIGMAR1HRH3SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL25754672 | 0.85 | HRH3 (0.37) | SIGMAR1HRH3SLC6A2HRH1CHRM2 | |
| SCHEMBL17528528 | 0.85 | SIGMAR1 (0.47) | SIGMAR1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL17526293 | 0.85 | SIGMAR1 (0.47) | SIGMAR1SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016020137-A1 | NITROGEN-CONTAINING COMPOUNDS SUITABLE FOR USE IN THE PRODUCTION OF POLYURETHANES | EVONIK DEGUSSA GMBH (DE) | 2016-02-11 | — | — | WO | disclosed |