Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 2/20 | 0.39 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.38 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.38 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17526731 | 1.00 | TSHR (0.50) | TSHRCYP3A4ATMTDP1L3MBTL1 | |
| SCHEMBL17526467 | 0.94 | TSHR (0.52) | TSHRCYP3A4ATMTDP1L3MBTL1 | |
| SCHEMBL17526581 | 0.94 | TSHR (0.52) | TSHRCYP3A4ATMTDP1L3MBTL1 | |
| SCHEMBL2499138 | 0.92 | L3MBTL1 (0.54) | TSHRCYP3A4ATMTDP1L3MBTL1 | |
| SCHEMBL495714 | 0.89 | L3MBTL1 (0.51) | TSHRCYP3A4ATMTDP1L3MBTL1 | |
| SCHEMBL493927 | 0.89 | L3MBTL1 (0.51) | TSHRCYP3A4ATMTDP1L3MBTL1 | |
| SCHEMBL494253 | 0.89 | L3MBTL1 (0.51) | TSHRCYP3A4ATMTDP1L3MBTL1 | |
| SCHEMBL495278 | 0.89 | L3MBTL1 (0.51) | TSHRCYP3A4ATMTDP1L3MBTL1 | |
| SCHEMBL494337 | 0.89 | L3MBTL1 (0.51) | TSHRCYP3A4ATMTDP1L3MBTL1 | |
| SCHEMBL494032 | 0.89 | L3MBTL1 (0.51) | TSHRCYP3A4ATMTDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160039879-A1 | NOVEL CYCLOSPORIN DERIVATIVES AND USES THEREOF | S&T GLOBAL INC. (US) | 2016-02-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160039879-A1 | NOVEL CYCLOSPORIN DERIVATIVES AND USES THEREOF | FKBP1B, MALT1, FKBP5 | TSHR 4131/4885CYP3A4 1071/4885ATM 4605/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.