Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | GPR84 | Q9NQS5 | 5/20 | 0.42 |
| ▸ | FAAH | O00519 | 2/20 | 0.40 |
| ▸ | FDPS | P14324 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.36 |
| ▸ | ACACB | O00763 | 1/20 | 0.36 |
| ▸ | ACACA | Q13085 | 1/20 | 0.36 |
| ▸ | PSMD14 | O00487 | 2/20 | 0.36 |
| ▸ | PLA2G1B | P04054 | 2/20 | 0.36 |
| ▸ | MMP2 | P08253 | 2/20 | 0.36 |
| ▸ | ATG4B | Q9Y4P1 | 2/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | RAD52 | P43351 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17526825 | 1.00 | FFAR4 (0.44) | FFAR4FFAR1NFKB1GPR84FAAH | |
| SCHEMBL17526777 | 0.96 | FFAR4 (0.40) | FFAR4FFAR1NFKB1GPR84FAAH | |
| SCHEMBL17526718 | 0.96 | FFAR4 (0.40) | FFAR4FFAR1NFKB1GPR84FAAH | |
| SCHEMBL1679202 | 0.82 | TSHR (0.50) | ALDH1A1TSHR | |
| SCHEMBL5508330 | 0.80 | EPHX1 (0.50) | ALDH1A1TSHR | |
| SCHEMBL7776706 | 0.80 | EPHX1 (0.50) | ALDH1A1TSHR | |
| SCHEMBL5504517 | 0.80 | EPHX1 (0.50) | ALDH1A1TSHR | |
| SCHEMBL41714 | 0.80 | EPHX1 (0.50) | ALDH1A1TSHR | |
| SCHEMBL668098 | 0.80 | EPHX1 (0.50) | ALDH1A1TSHR | |
| SCHEMBL15171894 | 0.80 | EPHX1 (0.50) | ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160039879-A1 | NOVEL CYCLOSPORIN DERIVATIVES AND USES THEREOF | S&T GLOBAL INC. (US) | 2016-02-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160039879-A1 | NOVEL CYCLOSPORIN DERIVATIVES AND USES THEREOF | FKBP1B, MALT1, FKBP5 | FFAR4 2413/4885FFAR1 2686/4885NFKB1 846/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.