SCHEMBL1679202

SCHEMBL1679202

CCCCCNC(C)(C)C

nearest known ligand 0.50

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.50
ALDH1A1 P00352 1/20 0.50
EPHX1 P07099 10/20 0.46
ADH1B P00325 2/20 0.40
ADH1C P00326 2/20 0.40
ADH1A P07327 2/20 0.40
ADH7 P40394 2/20 0.40
ADH4 P08319 1/20 0.40
THRB P10828 1/20 0.39
HRH4 Q9H3N8 2/20 0.38
HRH3 Q9Y5N1 2/20 0.38
POLB P06746 1/20 0.38
PPARA Q07869 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL668300 0.97 EPHX1 (0.50) TSHRALDH1A1EPHX1ADH1BADH1C
SCHEMBL41714 0.97 EPHX1 (0.50) TSHRALDH1A1EPHX1ADH1BADH1C
SCHEMBL8421553 0.97 EPHX1 (0.50) TSHRALDH1A1EPHX1ADH1BADH1C
SCHEMBL668098 0.97 EPHX1 (0.50) TSHRALDH1A1EPHX1ADH1BADH1C
SCHEMBL5508330 0.97 EPHX1 (0.50) TSHRALDH1A1EPHX1ADH1BADH1C
SCHEMBL15171894 0.97 EPHX1 (0.50) TSHRALDH1A1EPHX1ADH1BADH1C
Hydrochloric Acid SCHEMBL2364220 0.97 TSHR (0.48) TSHRALDH1A1EPHX1ADH1BADH1C
SCHEMBL7776706 0.97 EPHX1 (0.50) TSHRALDH1A1EPHX1ADH1BADH1C
SCHEMBL5504517 0.97 EPHX1 (0.50) TSHRALDH1A1EPHX1ADH1BADH1C
SCHEMBL7777014 0.97 EPHX1 (0.50) TSHRALDH1A1EPHX1ADH1BADH1C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 113 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3740613-B1 PROCESS FOR MAKING PAPER WITH IMPROVED FILLER RETENTION AND OPACITY WHILE MAINTAINING WET TENSILE STRENGTH SOLENIS TECH LP (US) 2023-07-26 EP claimed
US-5840977-A CYCLOHEXANOL UREA DERIVATIVE AS INTERMEDIATE FUJIREBIO INC. (JP) 1998-11-24 US claimed
EP-0612740-A1 Methods of producing pantothenic acid derivative and its starting materials for producing the same FUJIREBIO Inc. (JP) 1994-08-31 EP claimed
US-20240239787-A1 COMPOUNDS FOR USE IN THE TREATMENT OF CANCER NANYANG TECHNOLOGICAL UNIVERSITY (SG) 2024-07-18 US disclosed
US-20240231230-A1 COMPOSITION FOR FORMING SILICON-CONTAINING RESIST UNDERLAYER FILM NISSAN CHEMICAL CORPORATION (JP) 2024-07-11 US disclosed
US-20230399292-A1 ANESTHETIC COMPOUNDS AND METHODS OF MAKING AND USING SAME TO TREAT OR PREVENT PAIN SYMPTOMS PTC Innovations, LLC 2023-12-14 US disclosed
US-20230399291-A1 ANESTHETIC COMPOUNDS AND METHODS OF MAKING AND USING SAME TO TREAT OR PREVENT PAIN SYMPTOMS PTC INNOVATIONS LLC (US) 2023-12-14 US disclosed
US-20230331761-A1 Aryl Glucoside Derivative, Preparation Method Therefor And Application Thereof SHANGHAI ZHEYE BIOTECHNOLOGY CO. LTD. (CN) 2023-10-19 US disclosed
US-11786493-B2 Anesthetic compounds and methods of making and using same to treat or prevent pain symptoms PTC Innovations, LLC (US) 2023-10-17 US disclosed
US-20230279023-A1 N/O-Linked Degrons and Degronimers for Protein Degradation C4 THERAPEUTICS, INC. (US) 2023-09-07 US disclosed
US-11685722-B2 Inhibition of Olig2 activity Curtana Pharmaceuticals, Inc. (US) 2023-06-27 US disclosed
EP-0612740-B1 Methods of producing pantothenic acid derivative and its starting materials for producing the same FUJIREBIO KK (JP) 1999-09-22 EP disclosed
US-5871572-A COLORANT, WATER, A WATER-SOLUBLE ORGANIC SOLVENT, AND PECTIC ACID SEIKO EPSON CORPORATION (JP) 1999-02-16 US disclosed
US-5840977-A CYCLOHEXANOL UREA DERIVATIVE AS INTERMEDIATE FUJIREBIO INC. (JP) 1998-11-24 US disclosed
EP-0838508-A2 Aqueous ink composition for use in an ink-jet printer SEIKO EPSON CORPORATION (JP) 1998-04-29 EP disclosed
US-5719298-A REACTING PANTOTHENIC ACID ACETONIDE WITH UREA COMPOUND IN THE PRESENCE OF ACYLATING AGENT FUJIREBIO INC. (JP) 1998-02-17 US disclosed
EP-0623578-B1 Process for the preparation of dichloroacetylchloride HOECHST AG (DE) 1997-08-13 EP disclosed
US-5433831-A Process for the preparation of dichloroacetyl chloride HOECHST AKTIENGESELLCHAFT (DE) 1995-07-18 US disclosed
EP-0623578-A1 Process for the preparation of dichloroacetylchloride HOECHST AKTIENGESELLSCHAFT (DE) 1994-11-09 EP disclosed
EP-0612740-A1 Methods of producing pantothenic acid derivative and its starting materials for producing the same FUJIREBIO Inc. (JP) 1994-08-31 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230399292-A1 ANESTHETIC COMPOUNDS AND METHODS OF MAKING AND USING SAME TO TREAT OR PREVENT PAIN SYMPTOMS OPRM1, OPRL1, OPRK1 TSHR 1465/4885ALDH1A1 676/4885EPHX1 204/4885
US-20230399291-A1 ANESTHETIC COMPOUNDS AND METHODS OF MAKING AND USING SAME TO TREAT OR PREVENT PAIN SYMPTOMS CHRM2, RXFP2, OPRM1 TSHR 2336/4885ALDH1A1 1968/4885EPHX1 404/4885
US-20230331761-A1 Aryl Glucoside Derivative, Preparation Method Therefor And Application Thereof SLC5A1, SLC5A2, SLC10A1 TSHR 3176/4885ALDH1A1 449/4885EPHX1 3381/4885
US-11685722-B2 Inhibition of Olig2 activity GLI2, ING2, GMFG TSHR 4810/4885ALDH1A1 1478/4885EPHX1 532/4885
US-20230279023-A1 N/O-Linked Degrons and Degronimers for Protein Degradation CRBN, CBL, STUB1 TSHR 1050/4885ALDH1A1 4548/4885EPHX1 4127/4885
US-20240239787-A1 COMPOUNDS FOR USE IN THE TREATMENT OF CANCER BRIX1, TP53, XPOT TSHR 2641/4885ALDH1A1 1975/4885EPHX1 3315/4885
US-11786493-B2 Anesthetic compounds and methods of making and using same to treat or prevent pain symptoms OPRM1, OPRL1, OPRK1 TSHR 2657/4885ALDH1A1 409/4885EPHX1 52/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.