Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.90 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.71 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.46 |
| ▸ | GMNN | O75496 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | THPO | P40225 | 1/20 | 0.46 |
| ▸ | MTOR | P42345 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CETP | P11597 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | UBE2N | P61088 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17526764 | 1.00 | LMNA (0.90) | LMNAALDH1A1CYP2D6CYP3A4SPHK1 | |
| SCHEMBL744748 | 1.00 | LMNA (0.90) | LMNAALDH1A1CYP2D6CYP3A4SPHK1 | |
| SCHEMBL15936480 | 1.00 | LMNA (0.90) | LMNAALDH1A1CYP2D6CYP3A4SPHK1 | |
| SCHEMBL22129666 | 0.97 | LMNA (0.95) | LMNAALDH1A1CYP2D6CYP3A4SPHK1 | |
| SCHEMBL22129709 | 0.97 | LMNA (0.95) | LMNAALDH1A1CYP2D6CYP3A4SPHK1 | |
| SCHEMBL9442816 | 0.97 | LMNA (0.95) | LMNAALDH1A1CYP2D6CYP3A4SPHK1 | |
| SCHEMBL5566930 | 0.97 | LMNA (0.95) | LMNAALDH1A1CYP2D6CYP3A4SPHK1 | |
| SCHEMBL21561335 | 0.97 | LMNA (0.95) | LMNAALDH1A1CYP2D6CYP3A4SPHK1 | |
| SCHEMBL3093827 | 0.97 | LMNA (0.95) | LMNAALDH1A1CYP2D6CYP3A4SPHK1 | |
| SCHEMBL22129707 | 0.97 | LMNA (0.95) | LMNAALDH1A1CYP2D6CYP3A4SPHK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160039879-A1 | NOVEL CYCLOSPORIN DERIVATIVES AND USES THEREOF | S&T GLOBAL INC. (US) | 2016-02-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160039879-A1 | NOVEL CYCLOSPORIN DERIVATIVES AND USES THEREOF | FKBP1B, MALT1, FKBP5 | LMNA 3497/4885ALDH1A1 2376/4885CYP2D6 213/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.