Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.36 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.35 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.35 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.35 |
| ▸ | FPR3 | P25089 | 1/20 | 0.35 |
| ▸ | FPR2 | P25090 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.34 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.34 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.34 |
| ▸ | LTA4H | P09960 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17528519 | 0.98 | KDM4E (0.37) | KDM4EHTTTSHRALDH1A1HRH3 | |
| SCHEMBL17526296 | 0.98 | HRH3 (0.36) | KDM4EHTTTSHRALDH1A1HRH3 | |
| SCHEMBL17528522 | 0.98 | HRH3 (0.36) | KDM4EHTTTSHRALDH1A1HRH3 | |
| SCHEMBL17528531 | 0.96 | HRH3 (0.36) | KDM4EHTTTSHRALDH1A1HRH3 | |
| SCHEMBL17528492 | 0.93 | SIGMAR1 (0.40) | KDM4ETSHRALDH1A1HRH3CARM1 | |
| SCHEMBL17528470 | 0.93 | HTR1A (0.40) | KDM4EHTTTSHRALDH1A1HRH3 | |
| SCHEMBL17528469 | 0.93 | HTR1A (0.40) | KDM4EHTTTSHRALDH1A1HRH3 | |
| SCHEMBL17528467 | 0.91 | KDM4E (0.41) | KDM4EHTTALDH1A1HRH3CARM1 | |
| SCHEMBL17528495 | 0.89 | HTR1A (0.40) | KDM4EHTTTSHRHRH3CARM1 | |
| SCHEMBL17528539 | 0.89 | SIGMAR1 (0.40) | KDM4ETSHRALDH1A1HRH3CARM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016020140-A2 | NITROGEN-CONTAINING COMPOUNDS SUITABLE FOR USE IN THE PRODUCTION OF POLYURETHANES | EVONIK DEGUSSA GMBH (DE) | 2016-02-11 | — | — | WO | disclosed |