Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 8/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.33 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.33 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17528498 | 1.00 | HRH3 (0.37) | HRH3SIGMAR1MAPTALDH1A1POLB | |
| SCHEMBL17528475 | 1.00 | HRH3 (0.37) | HRH3SIGMAR1MAPTALDH1A1POLB | |
| SCHEMBL17539388 | 0.98 | HRH3 (0.39) | HRH3SIGMAR1MAPTALDH1A1POLB | |
| SCHEMBL11199088 | 0.98 | HRH3 (0.39) | HRH3SIGMAR1MAPTALDH1A1POLB | |
| SCHEMBL13187858 | 0.95 | HRH3 (0.42) | HRH3SIGMAR1MAPTALDH1A1POLB | |
| SCHEMBL2842787 | 0.95 | HRH3 (0.42) | HRH3SIGMAR1MAPTALDH1A1POLB | |
| SCHEMBL17528502 | 0.90 | SIGMAR1 (0.33) | HRH3SIGMAR1MAPTALDH1A1POLB | |
| SCHEMBL17528500 | 0.88 | HRH3 (0.46) | HRH3SIGMAR1MAPTALDH1A1POLB | |
| SCHEMBL17526221 | 0.88 | HRH3 (0.46) | HRH3SIGMAR1MAPTALDH1A1POLB | |
| SCHEMBL16075891 | 0.86 | ALDH1A1 (0.45) | HRH3SIGMAR1ALDH1A1LMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016020140-A2 | NITROGEN-CONTAINING COMPOUNDS SUITABLE FOR USE IN THE PRODUCTION OF POLYURETHANES | EVONIK DEGUSSA GMBH (DE) | 2016-02-11 | — | — | WO | disclosed |