Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 2/20 | 0.55 |
| ▸ | DGKA | P23743 | 1/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.37 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.37 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | THRA | P10827 | 3/20 | 0.35 |
| ▸ | THRB | P10828 | 3/20 | 0.35 |
| ▸ | PAM | P19021 | 2/20 | 0.35 |
| ▸ | NAAA | Q02083 | 1/20 | 0.34 |
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KDM5A | P29375 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14157686 | 0.92 | DNM1 (0.65) | DNM1DGKAPRSS1PRSS2PRSS3 | |
| SCHEMBL14239733 | 0.88 | DNM1 (0.56) | DNM1DGKATSHRTHRBMAPT | |
| SCHEMBL21027067 | 0.87 | DNM1 (0.55) | DNM1DGKAPRSS1PRSS2PRSS3 | |
| SCHEMBL22063092 | 0.86 | DNM1 (0.54) | DNM1DGKAPRSS1PRSS2PRSS3 | |
| SCHEMBL17586414 | 0.86 | DNM1 (0.53) | DNM1DGKATSHRTHRBMAPT | |
| SCHEMBL21467209 | 0.86 | DNM1 (0.53) | DNM1DGKATSHRTHRBMAPT | |
| SCHEMBL17581848 | 0.85 | DNM1 (0.53) | DNM1TSHRTHRBMAPTALDH1A1 | |
| SCHEMBL21336568 | 0.85 | DNM1 (0.53) | DNM1TSHRTHRBMAPTALDH1A1 | |
| SCHEMBL18469356 | 0.83 | DNM1 (0.53) | DNM1DGKATSHRTHRBMAPT | |
| SCHEMBL21027716 | 0.83 | DNM1 (0.50) | DNM1DGKATSHRTHRBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2718261-B1 | COMPOUNDS FOR TARGETING DRUG DELIVERY AND ENHANCING SIRNA ACTIVITY | NITTO DENKO CORP (JP) | 2016-02-24 | — | — | EP | disclosed |