SCHEMBL14157686

SCHEMBL14157686

CCCCCCCCCCCCCC(=O)OCCN(CCOC(=O)CCCCCCCCCCCCC)C(=O)CSCCN(C)C

nearest known ligand 0.65

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
DNM1 Q05193 2/20 0.65
DGKA P23743 1/20 0.50
PRSS1 P07477 1/20 0.42
PRSS2 P07478 1/20 0.42
PRSS3 P35030 1/20 0.42
PAM P19021 2/20 0.40
NAAA Q02083 1/20 0.40
TSHR P16473 1/20 0.38
MAPT P10636 1/20 0.38
KDM5A P29375 1/20 0.38
LMNA P02545 2/20 0.38
ALDH1A1 P00352 1/20 0.38
THRA P10827 1/20 0.37
THRB P10828 1/20 0.37
KDM4E B2RXH2 1/20 0.37
DUSP3 P51452 1/20 0.37
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14239733 0.93 DNM1 (0.56) DNM1DGKATSHRMAPTALDH1A1
SCHEMBL21027067 0.92 DNM1 (0.55) DNM1DGKAPRSS1PRSS2PRSS3
SCHEMBL17528637 0.92 DNM1 (0.55) DNM1DGKAPRSS1PRSS2PRSS3
SCHEMBL22063092 0.91 DNM1 (0.54) DNM1DGKAPRSS1PRSS2PRSS3
SCHEMBL17586414 0.91 DNM1 (0.53) DNM1DGKATSHRMAPTALDH1A1
SCHEMBL21467209 0.91 DNM1 (0.53) DNM1DGKATSHRMAPTALDH1A1
SCHEMBL17581848 0.90 DNM1 (0.53) DNM1TSHRMAPTLMNAALDH1A1
SCHEMBL21336568 0.90 DNM1 (0.53) DNM1TSHRMAPTLMNAALDH1A1
SCHEMBL16133359 0.89 DNM1 (0.53) DNM1DGKAPRSS1PRSS2PRSS3
SCHEMBL18469356 0.88 DNM1 (0.53) DNM1DGKATSHRMAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 143 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12617754-B2 Process for synthesizing lipids BRISTOL-MYERS SQUIBB COMPANY (US) 2026-05-05 US disclosed
EP-4171579-B1 PROCESS FOR SYNTHESIZING LIPIDS BRISTOL MYERS SQUIBB CO (US) 2026-02-25 EP disclosed
US-12440445-B2 Fusogenic compounds for delivery of biologically active molecules NITTO DENKO CORPORATION (JP) 2025-10-14 US disclosed
US-20230250056-A1 PROCESS FOR SYNTHESIZING LIPIDS BRISTOL-MYERS SQUIBB COMPANY 2023-08-10 US disclosed
US-20230250056-A1 PROCESS FOR SYNTHESIZING LIPIDS BRISTOL-MYERS SQUIBB COMPANY 2023-08-10 US disclosed
EP-4171579-A1 PROCESS FOR SYNTHESIZING LIPIDS Bristol-Myers Squibb Company (US) 2023-05-03 EP disclosed
US-11633365-B2 Nucleic acid-containing lipid nanoparticle KYOWA KIRIN CO., LTD. (JP) 2023-04-25 US disclosed
US-20220233445-A1 FUSOGENIC COMPOUNDS FOR DELIVERY OF BIOLOGICALLY ACTIVE MOLECULES NITTO DENKO CORPORATION (JP) 2022-07-28 US disclosed
EP-2858974-B9 LIPIDS FOR THERAPEUTIC AGENT DELIVERY FORMULATIONS NITTO DENKO CORP (JP) 2022-07-20 EP disclosed
WO-2021262746-A1 PROCESS FOR SYNTHESIZING LIPIDS BRISTOL-MYERS SQUIBB COMPANY (US) 2021-12-30 WO disclosed
WO-2012170952-A9 COMPOUNDS FOR TARGETING DRUG DELIVERY AND ENHANCING SIRNA ACTIVITY NITTO DENKO CORPORATION (JP) 2013-02-21 WO disclosed
WO-2012170952-A9 COMPOUNDS FOR TARGETING DRUG DELIVERY AND ENHANCING SIRNA ACTIVITY NITTO DENKO CORPORATION (JP) 2013-02-21 WO disclosed
US-20130022665-A1 CATIONIC LIPIDS FOR THERAPEUTIC AGENT DELIVERY FORMULATIONS NITTO DENKO CORPORATION (JP) 2013-01-24 US disclosed
US-20130022665-A1 CATIONIC LIPIDS FOR THERAPEUTIC AGENT DELIVERY FORMULATIONS NITTO DENKO CORPORATION (JP) 2013-01-24 US disclosed
US-20130022665-A1 CATIONIC LIPIDS FOR THERAPEUTIC AGENT DELIVERY FORMULATIONS NITTO DENKO CORPORATION (JP) 2013-01-24 US disclosed
US-20130017249-A1 COMPOUNDS FOR TARGETING DRUG DELIVERY AND ENHANCING siRNA ACTIVITY NITTO DENKO CORPORATION (JP) 2013-01-17 US disclosed
US-20130017249-A1 COMPOUNDS FOR TARGETING DRUG DELIVERY AND ENHANCING siRNA ACTIVITY NITTO DENKO CORPORATION (JP) 2013-01-17 US disclosed
WO-2012170952-A2 COMPOUNDS FOR TARGETING DRUG DELIVERY AND ENHANCING SIRNA ACTIVITY NITTO DENKO CORPORATION (JP) 2012-12-13 WO disclosed
WO-2012170957-A2 RETINOID-LIPOSOMES FOR ENHANCING MODULATION OF HSP47 EXPRESSION NITTO DENKO CORPORATION (JP) 2012-12-13 WO disclosed
WO-2012170952-A2 COMPOUNDS FOR TARGETING DRUG DELIVERY AND ENHANCING SIRNA ACTIVITY NITTO DENKO CORPORATION (JP) 2012-12-13 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230250056-A1 PROCESS FOR SYNTHESIZING LIPIDS PLIN1, SREBF1, SREBF2 DNM1 1086/4885DGKA 119/4885PRSS1 1007/4885
US-20130022665-A1 CATIONIC LIPIDS FOR THERAPEUTIC AGENT DELIVERY FORMULATIONS SGMS1, SGMS2, S1PR3 DNM1 714/4885DGKA 2435/4885PRSS1 1682/4885
US-11633365-B2 Nucleic acid-containing lipid nanoparticle LIPA, LIPC, PNLIP DNM1 3155/4885DGKA 66/4885PRSS1 1163/4885
US-20130017249-A1 COMPOUNDS FOR TARGETING DRUG DELIVERY AND ENHANCING siRNA ACTIVITY LDLR, RARG, FABP4 DNM1 1133/4885DGKA 195/4885PRSS1 3232/4885
US-12617754-B2 Process for synthesizing lipids LIPC, PHOSPHO1, SGMS1 DNM1 273/4885DGKA 92/4885PRSS1 2805/4885
US-20220233445-A1 FUSOGENIC COMPOUNDS FOR DELIVERY OF BIOLOGICALLY ACTIVE MOLECULES FUS, NSF, FABP7 DNM1 285/4885DGKA 1812/4885PRSS1 1028/4885
US-12440445-B2 Fusogenic compounds for delivery of biologically active molecules FUS, NSF, FABP7 DNM1 285/4885DGKA 1812/4885PRSS1 1028/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.