SCHEMBL17529294

SCHEMBL17529294

C1=Cc2c(ccc3ncccc23)NC1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.48
KDM4E B2RXH2 4/20 0.48
CYP3A4 P08684 2/20 0.41
LMNA P02545 4/20 0.40
BLM P54132 3/20 0.40
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
HIF1A Q16665 2/20 0.40
HSP90AA1 P07900 1/20 0.40
HSP90AB1 P08238 1/20 0.40
HTT P42858 1/20 0.40
SMN1; SMN2 Q16637 3/20 0.36
ERN1 O75460 1/20 0.35
NCOA1 Q15788 2/20 0.34
POLB P06746 4/20 0.33
GAA P10253 2/20 0.33
RECQL P46063 2/20 0.33
MCL1 Q07820 2/20 0.33
TDP1 Q9NUW8 2/20 0.33
L3MBTL1 Q9Y468 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2630611 0.75 CCR1 (0.50) MAPTKDM4ECYP3A4LMNAHIF1A
SCHEMBL70023 0.73 MAPT (0.48) MAPTKDM4ECYP3A4LMNABLM
SCHEMBL12219434 0.72 MAPT (0.52) MAPTKDM4ECYP3A4LMNABLM
Bromide SCHEMBL28730172 0.72 MAPT (0.47) MAPTKDM4ECYP3A4LMNABLM
SCHEMBL30003732 0.69 MAPT (0.47) MAPTKDM4ECYP3A4LMNABLM
SCHEMBL217044 0.69 MAPT (1.00) MAPTKDM4ECYP3A4LMNABLM
SCHEMBL29967313 0.67 CYP1A2 (0.31) SMN1; SMN2CYP1A2
SCHEMBL1938638 0.67 CYP1A2 (0.31) SMN1; SMN2CYP1A2
SCHEMBL5937225 0.67 MAPT (0.44) MAPTKDM4ECYP3A4LMNABLM
Hydrochloric Acid SCHEMBL28420480 0.66 MAPT (0.94) MAPTKDM4ECYP3A4LMNABLM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10937970-B2 Compound and photoelectric device, image sensor and electronic device including the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2021-03-02 US disclosed
US-20190131541-A1 COMPOUND AND PHOTOELECTRIC DEVICE, IMAGE SENSOR AND ELECTRONIC DEVICE INCLUDING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2019-05-02 US disclosed
EP-2197979-B1 NOVEL COMPOUND FOR ORGANIC PHOTOELECTRIC DEVICE AND ORGANIC PHOTOELECTRIC DEVICE INCLUDING THE SAME CHEIL IND INC (KR) 2016-12-07 EP disclosed
EP-2358765-B1 IMIDIZED POLYMERS CONTAINING LUMINESCENT GROUPS AND METHOD FOR OBTAINING THEM ENI SPA (IT) 2016-02-24 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10937970-B2 Compound and photoelectric device, image sensor and electronic device including the same NCS1, CYP19A1, CYP1A1 MAPT 4064/4885KDM4E 775/4885CYP3A4 110/4885
US-20190131541-A1 COMPOUND AND PHOTOELECTRIC DEVICE, IMAGE SENSOR AND ELECTRONIC DEVICE INCLUDING THE SAME NCS1, CYP19A1, CYP1A1 MAPT 4064/4885KDM4E 775/4885CYP3A4 110/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.