SCHEMBL70023

SCHEMBL70023

C1=Cc2ccc3ncccc3c2NC1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.48
KDM4E B2RXH2 1/20 0.48
CYP3A4 P08684 2/20 0.41
LMNA P02545 3/20 0.40
HIF1A Q16665 2/20 0.40
BLM P54132 2/20 0.40
MEN1 O00255 1/20 0.40
HSP90AA1 P07900 1/20 0.40
HSP90AB1 P08238 1/20 0.40
HTT P42858 1/20 0.40
KMT2A Q03164 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.36
ERN1 O75460 1/20 0.35
NCOA1 Q15788 2/20 0.34
ADRB2 P07550 1/20 0.33
NCF1 P14598 1/20 0.33
NCOA3 Q9Y6Q9 1/20 0.33
TSHR P16473 2/20 0.33
CYP1A2 P05177 1/20 0.33
POLB P06746 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bromide SCHEMBL28730172 0.98 MAPT (0.47) MAPTKDM4ECYP3A4LMNAHIF1A
SCHEMBL5937225 0.86 MAPT (0.44) MAPTKDM4ECYP3A4LMNAHIF1A
SCHEMBL30081188 0.80 KDM4E (0.39) MAPTKDM4ESMN1; SMN2ERN1ADRB2
SCHEMBL5736513 0.77 MAPT (0.42) MAPTKDM4ECYP3A4LMNAHIF1A
SCHEMBL208503 0.77 MAPT (0.48) MAPTKDM4ECYP3A4LMNAHIF1A
SCHEMBL10339659 0.75 MAPT (0.43) MAPTKDM4ECYP3A4LMNAHIF1A
SCHEMBL29639994 0.74 ALDH1A1 (0.39) MAPTKDM4ECYP3A4LMNAHIF1A
SCHEMBL17529294 0.73 MAPT (0.48) MAPTKDM4ECYP3A4LMNAHIF1A
SCHEMBL1644904 0.73 LMNA (0.48) MAPTKDM4ECYP3A4LMNAHIF1A
SCHEMBL13791237 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 106 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240155939-A1 HETEROCYCLIC AROMATIC AMINE COMPOUND AND ELECTROLUMINESCENCE USING THE SAME WUHAN TIANMA MICRO-ELECTRONICS CO., LTD. (CN) 2024-05-09 US claimed
CN-112480112-B Method for synthesizing substituted dihydrophenanthroline compound 浙江工业大学 2021-10-15 CN claimed
CN-112480112-A Method for synthesizing substituted dihydrophenanthroline compound 浙江工业大学 2021-03-12 CN claimed
CN-102887915-A Heteronuclear bimetallic complex light-emitting material and preparation method and application thereof UNIV JIAYING 2013-01-23 CN claimed
JP-2005523717-A 2005-08-11 JP claimed
EP-1499705-A2 MICROFERMENTORS FOR RAPID SCREENING AND ANALYSIS OF BIOCHEMICAL PROCESSES Massachusetts Institute of Technology (US) 2005-01-26 EP claimed
WO-2003093406-A2 MICROFERMENTORS FOR RAPID SCREENING AND ANALYSIS OF BIOCHEMICAL PROCESSES MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2003-11-13 WO claimed
US-20250255096-A1 LIGHT EMITTING DEVICE AND LIGHT EMITTING DISPLAY DEVICE LG DISPLAY CO., LTD. (KR) 2025-08-07 US disclosed
CN-111138463-B Organic electroluminescent device and polycyclic compound for organic electroluminescent device 三星显示有限公司 2025-02-25 CN disclosed
CN-118895063-A Ink composition and display device 三星显示有限公司 2024-11-05 CN disclosed
CN-118580208-A Light-emitting element and amine compound for light-emitting element 三星显示有限公司 2024-09-03 CN disclosed
CN-118290453-A Light-emitting element and condensed polycyclic compound for light-emitting element 三星显示有限公司 2024-07-05 CN disclosed
US-20240155939-A1 HETEROCYCLIC AROMATIC AMINE COMPOUND AND ELECTROLUMINESCENCE USING THE SAME WUHAN TIANMA MICRO-ELECTRONICS CO., LTD. (CN) 2024-05-09 US disclosed
US-5026828-A Releasing undesired proteins, followed by releasing hepatitis B; diafiltration MERCK & CO., INC. (US) 1991-06-25 US disclosed
US-5011915-A Centrifuging yeast membrane extract, then diafiltation in guanidine hydrochloride solution, solubilizing with denaturing agent and reducing agent MERCK & CO., INC. (US) 1991-04-30 US disclosed
EP-0340837-A1 Recombinant GAG precursor of HIV, product, process, and use as aids vaccine MERCK & CO. INC. (US) 1989-11-08 EP disclosed
EP-0315242-A2 Process for purifying recombinant hepatitis antigens MERCK & CO. INC. (US) 1989-05-10 EP disclosed
EP-0314240-A2 Process for purifying recombinant hepatitis antigens MERCK & CO. INC. (US) 1989-05-03 EP disclosed
EP-0312164-A1 Purification of recombinant epstein-barr virus antigens from vero cells, yeast cells or L cells MERCK & CO. INC. (US) 1989-04-19 EP disclosed
EP-0280470-A1 Method of purifying recombinant pres-1/S-2/S hepatitis B antigen from yeast MERCK & CO. INC. (US) 1988-08-31 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240155939-A1 HETEROCYCLIC AROMATIC AMINE COMPOUND AND ELECTROLUMINESCENCE USING THE SAME CCNL2, CHRM1, AHR MAPT 4173/4885KDM4E 2787/4885CYP3A4 1775/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.