Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11575237 | 0.83 | TDP1 (0.38) | L3MBTL1TDP1TP53ALDH1A1LMNA | |
| SCHEMBL11873084 | 0.83 | TDP1 (0.50) | L3MBTL1TDP1TP53ALDH1A1LMNA | |
| SCHEMBL28606713 | 0.83 | BRD4 (0.45) | TDP1TP53ALDH1A1TRPA1KDM4E | |
| SCHEMBL6432106 | 0.82 | CYP2A6 (0.41) | L3MBTL1TDP1ALDH1A1LMNAPOLB | |
| SCHEMBL10686492 | 0.81 | LMNA (0.44) | TDP1TP53ALDH1A1LMNATRPA1 | |
| SCHEMBL16019390 | 0.75 | TDP1 (0.34) | TDP1TP53ALDH1A1TRPA1 | |
| SCHEMBL801935 | 0.73 | ALDH1A1 (0.49) | L3MBTL1TDP1ALDH1A1LMNAGAA | |
| SCHEMBL29407001 | 0.72 | ALDH1A1 (0.50) | TDP1TP53ALDH1A1LMNATRPA1 | |
| SCHEMBL293173 | 0.72 | ALDH1A1 (0.50) | TDP1TP53ALDH1A1LMNATRPA1 | |
| SCHEMBL11128225 | 0.72 | TDP1 (0.50) | L3MBTL1TDP1TP53ALDH1A1TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2763968-B1 | HERBICIDAL PYRIDAZINONE DERIVATIVES | SYNGENTA LTD (GB) | 2016-02-24 | — | — | EP | disclosed |