Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.38 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphoric Acid SCHEMBL29820 | 0.87 | ALDH1A1 (0.41) | POLBMEN1KMT2AALDH1A1TSHR | |
| Phosphoric Acid SCHEMBL900121 | 0.86 | POLB (0.38) | POLBMEN1KMT2AALDH1A1LPAR2 | |
| Phosphoric Acid SCHEMBL27878548 | 0.84 | ALDH1A1 (0.39) | POLBMEN1KMT2AALDH1A1LPAR2 | |
| Phosphoric Acid SCHEMBL5090654 | 0.84 | ALDH1A1 (0.39) | POLBMEN1KMT2AALDH1A1LPAR2 | |
| Phosphoric Acid SCHEMBL17187059 | 0.84 | ALDH1A1 (0.39) | POLBMEN1KMT2AALDH1A1LPAR2 | |
| Phosphoric Acid SCHEMBL27451943 | 0.84 | ALDH1A1 (0.39) | POLBMEN1KMT2AALDH1A1LPAR2 | |
| Phosphoric Acid SCHEMBL27925652 | 0.84 | ALDH1A1 (0.39) | POLBMEN1KMT2AALDH1A1LPAR2 | |
| Phosphoric Acid SCHEMBL17187057 | 0.84 | ALDH1A1 (0.39) | POLBMEN1KMT2AALDH1A1LPAR2 | |
| Phosphoric Acid SCHEMBL1478991 | 0.84 | ALDH1A1 (0.39) | POLBMEN1KMT2AALDH1A1LPAR2 | |
| Phosphoric Acid SCHEMBL10873645 | 0.84 | POLB (0.36) | POLBMEN1KMT2AALDH1A1LPAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106189469-B | Aqueous coating composition having low or zero VOC and comprising encapsulated or polymer adsorbed pigment and reduced binder | 罗门哈斯公司 | 2020-10-30 | — | — | CN | disclosed |
| US-10703928-B2 | Aqueous coating compositions having low or zero VOCs and comprising encapsulated or polymer adsorbed pigments and letdown binders | ROHM AND HAAS COMPANY (US) | 2020-07-07 | — | — | US | disclosed |
| US-20170283627-A1 | AQUEOUS COATING COMPOSITIONS HAVING LOW OR ZERO VOCS AND COMPRISING ENCAPSULATED OR POLYMER ADSORBED PIGMENTS AND LETDOWN BINDERS | ROHM AND HAAS COMPANY | 2017-10-05 | — | — | US | disclosed |
| EP-2990445-B1 | AQUEOUS COATING COMPOSITIONS HAVING LOW OR ZERO VOCS AND COMPRISING ENCAPSULATED OR POLYMER ADSORBED PIGMENTS AND LETDOWN BINDERS | ROHM & HAAS (US) | 2017-05-03 | — | — | EP | disclosed |
| EP-2990445-A1 | AQUEOUS COATING COMPOSITIONS HAVING LOW OR ZERO VOCS AND COMPRISING ENCAPSULATED OR POLYMER ADSORBED PIGMENTS AND LETDOWN BINDERS | Rohm and Haas Company (US) | 2016-03-02 | — | — | EP | disclosed |