SCHEMBL175302

SCHEMBL175302

C=CCOC(=O)C(C)=CO

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.40
CYP3A4 P08684 1/20 0.38
TDP1 Q9NUW8 1/20 0.37
MAPT P10636 4/20 0.36
CACNA1B Q00975 1/20 0.36
APBA1 Q02410 1/20 0.36
ALDH1A1 P00352 6/20 0.33
PTP4A3 O75365 2/20 0.33
PTP4A1 Q93096 2/20 0.33
HSD17B10 Q99714 2/20 0.33
PTP4A2 Q12974 1/20 0.33
MEN1 O00255 3/20 0.31
KMT2A Q03164 3/20 0.31
MAPK1 P28482 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
KDM4E B2RXH2 2/20 0.30
TP53 P04637 1/20 0.30
HPGD P15428 1/20 0.30
PKM P14618 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL45287 0.84 TSHR (0.41) TSHRCYP3A4TDP1MAPTCACNA1B
SCHEMBL9241885 0.84 TSHR (0.41) TSHRCYP3A4TDP1MAPTCACNA1B
SCHEMBL524629 0.84 TSHR (0.41) TSHRCYP3A4TDP1MAPTCACNA1B
SCHEMBL8212517 0.81 TSHR (0.39) TSHRCYP3A4TDP1MAPTCACNA1B
SCHEMBL8632787 0.81 MAPT (0.39) TSHRCYP3A4TDP1MAPTCACNA1B
SCHEMBL642158 0.81 MAPT (0.39) TSHRCYP3A4TDP1MAPTCACNA1B
SCHEMBL6536449 0.81 TSHR (0.39) TSHRCYP3A4TDP1MAPTCACNA1B
SCHEMBL3264769 0.81 TSHR (0.39) TSHRCYP3A4TDP1MAPTCACNA1B
SCHEMBL2066539 0.81 TSHR (0.39) TSHRCYP3A4TDP1MAPTCACNA1B
SCHEMBL29710697 0.79

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2271 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114456070-B Polymerization inhibition method in acrylic acid substance separation process 广东华锦达新材科技有限公司 2024-05-14 CN claimed
CN-115181272-A Preparation method of modified MQ resin and acrylate adhesive prepared by using same 黑龙江省科学院石油化学研究院 2022-10-14 CN claimed
US-11319392-B2 Compositions and methods to antibacterial nanogel and hydrolytically stable antibacterial nanogel for dental compositions DENTSPLY SIRONA INC. (US) 2022-05-03 US claimed
EP-3883520-A1 COMPOSITIONS AND METHODS TO ANTIBACTERIAL NANOGEL AND HYDROLYTICALLY STABLE ANTIBACTERIAL NANOGEL FOR DENTAL COMPOSITIONS DENTSPLY SIRONA Inc. (US) 2021-09-29 EP claimed
WO-2021050568-A1 NANOPARTICLES FOR SELECTIVE TISSUE OR CELLULAR UPTAKE YALE UNIVERSITY (US) 2021-03-18 WO claimed
US-20200157266-A1 COMPOSITIONS AND METHODS TO ANTIBACTERIAL NANOGEL AND HYDROLYTICALLY STABLE ANTIBACTERIAL NANOGEL FOR DENTAL COMPOSITIONS DENTSPLY SIRONA INC. (US) 2020-05-21 US claimed
CN-110023423-A Optical coating with low refractive index 巴斯夫涂料有限公司 2019-07-16 CN claimed
EP-2598518-B1 PRE-POLYMER PREPARATIONS FOR CELL CULTURE COATINGS CORNING INC (US) 2019-01-30 EP claimed
US-9733519-B2 Composition for forming thermoset film having photo alignment properties NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2017-08-15 US claimed
CN-104119628-B Transparent PMMA particle powders toughener 彭朕财 2017-06-16 CN claimed
US-4165418-A PIGMENT DISPERSANT POLYMER CONTAINING HYDROXY, AMIDE AND ESTERIFIED EPOXIDE GROUPS IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) 1979-08-21 US claimed
US-4151227-A Acrylic graft copolymers and coating compositions thereof E. I. DU PONT DE NEMOURS AND COMPANY (US) 1979-04-24 US claimed
US-4120835-A Thermosetting acrylic enamel containing iron pyrophosphate E. I. DU PONT DE NEMOURS AND COMPANY (US) 1978-10-17 US claimed
US-4020216-A Coating composition for flexible substrates E. I. DU PONT DE NEMOURS AND COMPANY (US) 1977-04-26 US claimed
US-3998768-A Thermosetting powder coating composition of a blend of acrylic polymers having different glass transition temperatures and a blocked polyisocyanate cross-linking agent E. I. DU PONT DE NEMOURS AND COMPANY (US) 1976-12-21 US claimed
US-3993849-A Metal substrate coated with a thermosetting powder coating composition of an acrylic polymer, a hydroxy functional plasticizer and a blocked polyisocyanate cross-linking agent E. I. DU PONT DE NEMOURS AND COMPANY (US) 1976-11-23 US claimed
US-3979535-A THERMOSETTING ACRYLIC ENAMEL E. I. DU PONT DE NEMOURS AND COMPANY (US) 1976-09-07 US claimed
US-3979540-A WEATHERABILITY AND DURABILITY AS AUTOMOBILE ROOF COVERING E. I. DU PONT DE NEMOURS AND COMPANY (US) 1976-09-07 US claimed
US-3959554-A Aqueous thermosetting acrylic enamel for finishing flexible hydrocarbon rubber substrates E. I. DUPONT DE NEMOURS AND COMPANY (US) 1976-05-25 US claimed
US-3954588-A Electrocoating process for depositing a corrosion retardant layer on a metal substrate and sequentially electrocoating a cationic film-forming polymer coating E. I. DU PONT DE NEMOURS AND COMPANY (US) 1976-05-04 US claimed