SCHEMBL45287

SCHEMBL45287

C=CCOC(=O)C(C)=CC

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.41
CYP3A4 P08684 1/20 0.39
TDP1 Q9NUW8 1/20 0.38
MAPT P10636 3/20 0.37
CACNA1B Q00975 1/20 0.37
APBA1 Q02410 1/20 0.37
PTP4A3 O75365 2/20 0.37
PTP4A1 Q93096 2/20 0.37
PTP4A2 Q12974 1/20 0.37
ALDH1A1 P00352 6/20 0.34
HSD17B10 Q99714 2/20 0.34
MEN1 O00255 3/20 0.32
KMT2A Q03164 3/20 0.32
MAPK1 P28482 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
KDM4E B2RXH2 2/20 0.31
TP53 P04637 1/20 0.31
HPGD P15428 1/20 0.31
PKM P14618 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL524629 1.00 TSHR (0.41) TSHRCYP3A4TDP1MAPTCACNA1B
SCHEMBL9241885 0.86 TSHR (0.41) TSHRCYP3A4TDP1MAPTCACNA1B
SCHEMBL11526644 0.85 TDP1 (0.36) TSHRCYP3A4TDP1MAPTCACNA1B
SCHEMBL175302 0.84 TSHR (0.40) TSHRCYP3A4TDP1MAPTCACNA1B
SCHEMBL6536449 0.83 TSHR (0.39) TSHRCYP3A4TDP1MAPTCACNA1B
SCHEMBL8632787 0.83 MAPT (0.39) TSHRCYP3A4TDP1MAPTCACNA1B
SCHEMBL27543519 0.83 TSHR (0.39) TSHRCYP3A4TDP1MAPTCACNA1B
SCHEMBL2066539 0.83 TSHR (0.39) TSHRCYP3A4TDP1MAPTCACNA1B
SCHEMBL3264769 0.83 TSHR (0.39) TSHRCYP3A4TDP1MAPTCACNA1B
SCHEMBL642158 0.83 MAPT (0.39) TSHRCYP3A4TDP1MAPTCACNA1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1007 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250302678-A1 ABSORBENT ARTICLES INCLUDING PERFUME AND CYCLODEXTRINS PROCTER & GAMBLE (US) 2025-10-02 US claimed
US-12350136-B2 Absorbent articles including perfume and cyclodextrins THE PROCTER & GAMBLE COMPANY (US) 2025-07-08 US claimed
CN-117801341-B Graphene heat-conducting insulating silicon wafer and preparation method thereof 江苏诺德新材料股份有限公司 2024-07-09 CN claimed
CN-115181738-B Novel organic adhesive for embedding oleaphilic strain, and preparation method and application thereof 天津大学 2024-06-14 CN claimed
CN-110859755-B Marrow covering agent for treating dental pulp lesions, and preparation method and application thereof 中国科学院化学研究所 2024-05-17 CN claimed
CN-117801341-A Graphene heat-conducting insulating silicon wafer and preparation method thereof 江苏诺德新材料股份有限公司 2024-04-02 CN claimed
CN-117693320-A Large block for manufacturing dental prosthesis 株式会社哈斯 2024-03-12 CN claimed
CN-117624506-A 3D printing photosensitive resin and preparation method and application thereof 深圳市智能派科技有限公司 2024-03-01 CN claimed
CN-114478937-B Water-retaining polycarboxylate water reducer for machine-made sand concrete and preparation method thereof 厦门市建筑科学研究院有限公司 2024-03-01 CN claimed
EP-4049990-B1 IDENTITY-PROTECTED SYNTHETIC RESIN MIXTURES FOR FIXING TECHNOLOGY, THEIR PRODUCTION AND USE FISCHERWERKE GMBH & CO KG (DE) 2023-11-15 EP claimed
US-20030091612-A1 Antimicrobial polyolefin articles and methods for their preparation E.I. DUPONT DE NEMOURS AND COMPANY 2003-05-15 US claimed
US-20020169233-A1 In situ microencapsulated adhesive IPS ADHESIVES LLC 2002-11-14 US claimed
WO-2002062901-A1 DENTAL AND MEDICAL POLYMER COMPOSITES AND COMPOSITIONS VALLITTU PEKKA (FI) 2002-08-15 WO claimed
WO-2002020683-A2 IN SITU MICROENCAPSULATED ADHESIVE APPLETON PAPERS INC. (US) 2002-03-14 WO claimed
EP-0582223-B1 Thermoplastic resin composition KANEGAFUCHI CHEMICAL IND (JP) 1996-10-09 EP claimed
EP-0582223-A1 Thermoplastic resin composition KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1994-02-09 EP claimed
US-4762867-A ACRYLIC ACID, ACRYLATE ESTER COPOLYMERS MIXTURES WITH CEMENTS POLYRAND AB (SE) 1988-08-09 US claimed
US-4267310-A DISPERSION OF A MELTED POLYESTER OR -AMIDE IN AN APROTIC NONSOLVENT CONTAINING A WATER-SOLUBLE BLOCK OR GRAFT POLYMER; COOLING HERCULES INCORPORATED (US) 1981-05-12 US claimed
US-4225473-A Alkyd-monomer high-solids coating process E. I. DU PONT DE NEMOURS AND COMPANY (US) 1980-09-30 US claimed
US-4007306-A Method of applying aqueous coating compositions INMONT CORPORATION (US) 1977-02-08 US claimed