SCHEMBL3264769

SCHEMBL3264769

C=CCOC(=O)C(C)=CF

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.39
CYP3A4 P08684 1/20 0.37
TDP1 Q9NUW8 1/20 0.36
MAPT P10636 2/20 0.35
CACNA1B Q00975 1/20 0.35
APBA1 Q02410 1/20 0.35
PTP4A3 O75365 2/20 0.33
PTP4A1 Q93096 2/20 0.33
PTP4A2 Q12974 1/20 0.33
ALDH1A1 P00352 5/20 0.33
HSD17B10 Q99714 2/20 0.33
MEN1 O00255 1/20 0.31
MAPK1 P28482 1/20 0.31
KMT2A Q03164 1/20 0.31
THRB P10828 1/20 0.31
TP53 P04637 2/20 0.30
HIF1A Q16665 2/20 0.30
NPSR1 Q6W5P4 1/20 0.30
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL45287 0.83 TSHR (0.41) TSHRCYP3A4TDP1MAPTCACNA1B
SCHEMBL9241885 0.83 TSHR (0.41) TSHRCYP3A4TDP1MAPTCACNA1B
SCHEMBL524629 0.83 TSHR (0.41) TSHRCYP3A4TDP1MAPTCACNA1B
SCHEMBL175302 0.81 TSHR (0.40) TSHRCYP3A4TDP1MAPTCACNA1B
SCHEMBL27543519 0.79 TSHR (0.39) TSHRCYP3A4TDP1MAPTCACNA1B
SCHEMBL6536449 0.79 TSHR (0.39) TSHRCYP3A4TDP1MAPTCACNA1B
SCHEMBL2066539 0.79 TSHR (0.39) TSHRCYP3A4TDP1MAPTCACNA1B
SCHEMBL8632787 0.79 MAPT (0.39) TSHRCYP3A4TDP1MAPTCACNA1B
SCHEMBL642158 0.79 MAPT (0.39) TSHRCYP3A4TDP1MAPTCACNA1B
SCHEMBL8212517 0.79 TSHR (0.39) TSHRCYP3A4TDP1MAPTCACNA1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130078796-A1 PROCESS FOR MAKING A PATTERNED METAL OXIDE STRUCTURE AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2013-03-28 US claimed
US-20210189094-A1 LIQUID COATINGS INCLUDING EXPANDABLE GRAPHITE AMRIZE TECHNOLOGY SWITZERLAND LLC (CH) 2021-06-24 US disclosed
US-10941272-B2 Liquid coatings including expandable graphite Firestone Building Products Co., LLC (US) 2021-03-09 US disclosed
US-20190219455-A1 TIRE TEMPERATURE INDICATOR FIRESTONE BUILDING PRODUCTS COMPANY, LLC 2019-07-18 US disclosed
EP-3507112-A1 TIRE TEMPERATURE INDICATOR Bridgestone Americas Tire Operations, LLC (US) 2019-07-10 EP disclosed
US-20180305931-A1 LIQUID COATINGS INCLUDING EXPANDABLE GRAPHITE AMRIZE TECHNOLOGY SWITZERLAND LLC (CH) 2018-10-25 US disclosed
US-10017943-B1 Liquid coatings including expandable graphite Firestone Building Products Co., LLC (US) 2018-07-10 US disclosed
US-7803867-B2 Highly weatherable roof coatings containing aqueous fluoropolymer dispersions ARKEMA INC. (US) 2010-09-28 US disclosed
EP-1888836-A4 HIGHLY WEATHERABLE ROOF COATINGS CONTAINING AQUEOUS FLUOROPOLYMER DISPERSIONS ARKEMA INC (US) 2009-09-02 EP disclosed
EP-1069141-B1 Crosslinkable aqueous fluoropolymer based dispersions, their preparation and use ARKEMA INC (US) 2009-01-14 EP disclosed
EP-1888836-A2 HIGHLY WEATHERABLE ROOF COATINGS CONTAINING AQUEOUS FLUOROPOLYMER DISPERSIONS Arkema Inc. (US) 2008-02-20 EP disclosed
WO-2007030152-A2 HIGHLY WEATHERABLE ROOF COATINGS CONTAINING AQUEOUS FLUOROPOLYMER DISPERSIONS ARKEMA INC. (US) 2007-03-15 WO disclosed
US-20060264563-A1 Highly weatherable roof coatings containing aqueous fluoropolymer dispersions ARKEMA INC. 2006-11-23 US disclosed
US-6680357-B1 CURABLE MIXTURES OF VINYLIDENE FLUORIDE HOMO(CO)POLYMERS WITH HEXAFLUOROPROPYLENE, ACRYLIC POLYMERS AND CURING AGENTS, USED IN PAINTS, COATINGS OR FILMS HAVING SOLVENT, WEAR AND CHEMICAL RESISTANCE ATOFINA CHEMICALS, INC. 2004-01-20 US disclosed
EP-1069141-A1 Crosslinkable aqueous fluoropolymer based dispersions, their preparation and use Atofina Chemicals, Inc. (US) 2001-01-17 EP disclosed