Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XPO1 | O14980 | 1/20 | 0.41 |
| ▸ | CUL4A | Q13619 | 2/20 | 0.36 |
| ▸ | PGR | P06401 | 4/20 | 0.34 |
| ▸ | CNR2 | P34972 | 3/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | VEGFA | P15692 | 1/20 | 0.32 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.31 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.31 |
| ▸ | MME | P08473 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2484620 | 0.81 | MAPT (0.46) | XPO1L3MBTL1KDM4EMAPT | |
| SCHEMBL2482216 | 0.80 | XPO1 (0.39) | XPO1CUL4APGRCNR2CHRM3 | |
| SCHEMBL417011 | 0.80 | XPO1 (0.42) | XPO1CNR2L3MBTL1TARBP2MAPT | |
| SCHEMBL2484122 | 0.72 | XPO1 (0.36) | XPO1CUL4APGRCHRM3MAPT | |
| SCHEMBL2481393 | 0.70 | XPO1 (0.39) | XPO1CUL4ACNR2EPAS1CHRM3 | |
| SCHEMBL2484716 | 0.69 | CUL4A (0.41) | CUL4AKDM4EMEN1LMNAMAPT | |
| SCHEMBL2516005 | 0.68 | CNR2 (0.40) | PGRCNR2CHRM3LMNA | |
| SCHEMBL7572578 | 0.67 | RXRA (0.45) | CNR2L3MBTL1KDM4EMEN1LMNA | |
| SCHEMBL419322 | 0.67 | XPO1 (0.43) | XPO1CHRM3TARBP2KDM4EMAPT | |
| SCHEMBL2482567 | 0.66 | MAPK14 (0.38) | XPO1EPAS1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2376479-B1 | SUBSTITUTED FURANCARBOXAMIDES, AND USE THEREOF | AICURIS GMBH & CO KG (DE) | 2016-03-02 | — | — | EP | disclosed |