Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.36 |
| ▸ | CCR1 | P32246 | 3/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 9/20 | 0.35 |
| ▸ | MAPK11 | Q15759 | 3/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | DDR1 | Q08345 | 3/20 | 0.34 |
| ▸ | DDR2 | Q16832 | 3/20 | 0.34 |
| ▸ | PYGL | P06737 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.33 |
| ▸ | MAP3K20 | Q9NYL2 | 1/20 | 0.33 |
| ▸ | MAP3K4 | Q9Y6R4 | 1/20 | 0.33 |
| ▸ | CTSL | P07711 | 1/20 | 0.33 |
| ▸ | CTSS | P25774 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17532286 | 0.91 | ALDH1A1 (0.39) | ALDH1A1LMNAMAPTCCR1MAPK14 | |
| SCHEMBL19485653 | 0.91 | MAPK14 (0.37) | ACE2CCR1MAPK14MAPK11DDR1 | |
| SCHEMBL17834815 | 0.91 | MAPK14 (0.37) | ACE2CCR1MAPK14MAPK11DDR1 | |
| SCHEMBL22167227 | 0.89 | CCR1 (0.39) | ALDH1A1LMNAMAPTCCR1MAPK14 | |
| SCHEMBL17532282 | 0.89 | CCR1 (0.39) | ALDH1A1LMNAMAPTCCR1MAPK14 | |
| SCHEMBL17532294 | 0.89 | ACE2 (0.33) | ACE2CCR1MAPK14MAPK11DDR1 | |
| SCHEMBL17834664 | 0.88 | CCR1 (0.38) | ACE2CCR1MAPK1PYGLCTSL | |
| SCHEMBL17532296 | 0.86 | ALDH1A1 (0.35) | ALDH1A1LMNAMAPTCCR1MAPK1 | |
| SCHEMBL22167240 | 0.86 | ALDH1A1 (0.35) | ALDH1A1LMNAMAPTCCR1MAPK1 | |
| SCHEMBL19485628 | 0.86 | CCR1 (0.41) | ALDH1A1LMNAMAPTCCR1MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9839664-B2 | GLP-1 receptor modulators | CELGENE INTERNATIONAL II SÀRL (CH) | 2017-12-12 | — | — | US | disclosed |
| US-9839664-B2 | GLP-1 receptor modulators | CELGENE INTERNATIONAL II SÀRL (CH) | 2017-12-12 | — | — | US | disclosed |
| US-20170216392-A1 | NOVEL GLP-1 RECEPTOR MODULATORS | RECEPTOS LLC | 2017-08-03 | — | — | US | disclosed |
| US-20170216392-A1 | NOVEL GLP-1 RECEPTOR MODULATORS | RECEPTOS LLC | 2017-08-03 | — | — | US | disclosed |
| US-9474755-B2 | GLP-1 receptor modulators | CELGENE INTERNATIONAL II SARL (CH) | 2016-10-25 | — | — | US | disclosed |
| US-9474755-B2 | GLP-1 receptor modulators | CELGENE INTERNATIONAL II SARL (CH) | 2016-10-25 | — | — | US | disclosed |
| US-20160038487-A1 | NOVEL GLP-1 RECEPTOR MODULATORS | RECEPTOS LLC | 2016-02-11 | — | — | US | disclosed |
| US-20160038487-A1 | NOVEL GLP-1 RECEPTOR MODULATORS | RECEPTOS LLC | 2016-02-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170216392-A1 | NOVEL GLP-1 RECEPTOR MODULATORS | GLP1R, GIPR, NPY1R | ALDH1A1 4730/4885LMNA 2896/4885MAPT 3992/4885 |
| US-20160038487-A1 | NOVEL GLP-1 RECEPTOR MODULATORS | GLP1R, GIPR, NPY1R | ALDH1A1 4730/4885LMNA 2896/4885MAPT 3992/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.