Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MAPK11 | Q15759 | 2/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.37 |
| ▸ | PYGL | P06737 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.36 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.35 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.34 |
| ▸ | MC4R | P32245 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17532282 | 1.00 | CCR1 (0.39) | CCR1ALDH1A1LMNAMAPTMAPK11 | |
| SCHEMBL17532286 | 0.93 | ALDH1A1 (0.39) | CCR1ALDH1A1LMNAMAPTMAPK11 | |
| SCHEMBL19485744 | 0.91 | ENPP2 (0.39) | MAPK11MAPK14MAPK1PYGLS1PR1 | |
| SCHEMBL17834495 | 0.91 | ENPP2 (0.39) | MAPK11MAPK14MAPK1PYGLS1PR1 | |
| SCHEMBL17532293 | 0.89 | ALDH1A1 (0.36) | CCR1ALDH1A1LMNAMAPTMAPK11 | |
| SCHEMBL17468520 | 0.89 | MAPK14 (0.35) | CCR1MAPK11MAPK14PYGLS1PR1 | |
| SCHEMBL22167389 | 0.89 | MAPK14 (0.35) | CCR1MAPK11MAPK14PYGLS1PR1 | |
| SCHEMBL22167240 | 0.88 | ALDH1A1 (0.35) | CCR1ALDH1A1LMNAMAPTMAPK1 | |
| SCHEMBL17532296 | 0.88 | ALDH1A1 (0.35) | CCR1ALDH1A1LMNAMAPTMAPK1 | |
| SCHEMBL17834816 | 0.88 | CCR1 (0.41) | CCR1ALDH1A1LMNAMAPTMAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3172199-B1 | PYRIMIDINE DERIVATIVES AS GLP-1 RECEPTOR MODULATORS | CELGENE INT II SARL (CH) | 2020-07-01 | — | — | EP | disclosed |