Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.34 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.34 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.34 |
| ▸ | PDK2 | Q15119 | 3/20 | 0.33 |
| ▸ | MYC | P01106 | 1/20 | 0.33 |
| ▸ | MAX | P61244 | 1/20 | 0.33 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.32 |
| ▸ | FABP3 | P05413 | 1/20 | 0.32 |
| ▸ | FABP4 | P15090 | 1/20 | 0.32 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | GLA | P06280 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17454740 | 0.97 | PDK2 (0.35) | SIRT2SIRT1ALKPDK2MYC | |
| SCHEMBL17759868 | 0.94 | PDK2 (0.36) | ALKPDK2PTGER4TDP1KDM4E | |
| SCHEMBL14681411 | 0.93 | PDK2 (0.37) | ALKPDK2MYCMAXPTGER4 | |
| SCHEMBL17759926 | 0.88 | CDC25B (0.43) | ALKTDP1KDM4EMEN1GLA | |
| SCHEMBL17468822 | 0.87 | PDK2 (0.40) | SIRT2SIRT1PDK2PTGER4MEN1 | |
| SCHEMBL17759698 | 0.87 | PDK2 (0.39) | SIRT2SIRT1ALKPDK2AKR1C3 | |
| SCHEMBL17759560 | 0.86 | ALDH1A1 (0.43) | PDK2KDM4EMEN1MAPTKMT2A | |
| SCHEMBL17760144 | 0.86 | CDC25B (0.41) | SIRT2SIRT1ALKAKR1C3TDP1 | |
| SCHEMBL17760234 | 0.86 | CDC25B (0.41) | SIRT2SIRT1ALKAKR1C3TDP1 | |
| SCHEMBL17547202 | 0.86 | ALK (0.42) | SIRT2SIRT1ALKMYCMAX |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016028110-A1 | A PLURALITY OF HOST MATERIALS AND AN ORGANIC ELECTROLUMINESCENCE DEVICE COMPRISING THE SAME | ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) | 2016-02-25 | — | — | WO | disclosed |