Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 11/20 | 0.39 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.37 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.37 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 2/20 | 0.34 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.34 |
| ▸ | STK10 | O94804 | 1/20 | 0.34 |
| ▸ | SLK | Q9H2G2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | APAF1 | O14727 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | XBP1 | P17861 | 1/20 | 0.33 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | GALK1 | P51570 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17454691 | 0.91 | PDK2 (0.41) | PDK2ALKSTK10SLKMEN1 | |
| SCHEMBL17759523 | 0.91 | ALDH1A1 (0.38) | PDK2SIRT2SIRT1BRD4MEN1 | |
| SCHEMBL25125291 | 0.90 | SIRT2 (0.40) | PDK2SIRT2SIRT1AKR1C3STK10 | |
| SCHEMBL29892218 | 0.90 | PDK2 (0.39) | PDK2SIRT2SIRT1MEN1APAF1 | |
| SCHEMBL15713467 | 0.90 | PDK2 (0.39) | PDK2SIRT2SIRT1MEN1APAF1 | |
| SCHEMBL17760145 | 0.90 | CDC25B (0.41) | PDK2SIRT2SIRT1ALKBRD4 | |
| SCHEMBL16215960 | 0.89 | PDK2 (0.37) | PDK2 | |
| SCHEMBL17760046 | 0.88 | SIRT2 (0.37) | PDK2SIRT2SIRT1ALKAKR1C3 | |
| SCHEMBL17759868 | 0.88 | PDK2 (0.36) | PDK2ALKSTK10SLKMEN1 | |
| SCHEMBL22182374 | 0.87 | PDK2 (0.47) | PDK2SIRT2SIRT1BRD4STK10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016076629-A1 | A PLURALITY OF HOST MATERIALS AND AN ORGANIC ELECTROLUMINESCENCE DEVICE COMPRISING THE SAME | ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) | 2016-05-19 | — | — | WO | disclosed |