SCHEMBL17534868

SCHEMBL17534868

[c]1ncccc1-c1cccc2c1Cc1ccccc1-2

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PNMT P11086 1/20 0.42
NPC1 O15118 3/20 0.38
RAB9A P51151 3/20 0.38
DRD2 P14416 1/20 0.37
DRD4 P21917 1/20 0.37
DRD3 P35462 1/20 0.37
HTR7 P34969 1/20 0.35
HTR2B P41595 1/20 0.35
CDK1 P06493 1/20 0.33
CDK2 P24941 1/20 0.33
MAP3K9 P80192 1/20 0.33
MAP3K11 Q16584 1/20 0.33
KDR P35968 1/20 0.33
ADORA2A P29274 1/20 0.33
ADORA1 P30542 1/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA4 P22748 1/20 0.33
CA6 P23280 1/20 0.33
MAOA P21397 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30103334 0.76 PNMT (0.63) PNMTNPC1RAB9ADRD2DRD4
SCHEMBL524602 0.76 PNMT (0.63) PNMTNPC1RAB9ADRD2DRD4
SCHEMBL550235 0.75 PNMT (0.46) PNMTNPC1RAB9ADRD2DRD4
SCHEMBL2877998 0.74 PNMT (0.61) PNMTNPC1RAB9ADRD2DRD4
SCHEMBL27885618 0.70 PNMT (0.57) PNMTNPC1RAB9ADRD2DRD4
SCHEMBL31443024 0.70 PNMT (0.49) PNMTNPC1RAB9ADRD2DRD4
SCHEMBL28042398 0.69 CDK1 (0.54) PNMTNPC1RAB9ADRD2DRD4
SCHEMBL1115099 0.69 NISCH (0.41) NPC1RAB9ABCHEKDM4EMAPT
SCHEMBL4022045 0.69 PNMT (0.55) PNMTNPC1RAB9ADRD2DRD4
SCHEMBL31498305 0.69 CYP11B1 (0.52) PNMTNPC1RAB9AKDM4EMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 138 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4018870-B1 COMPONENTS OF ARTICLES OF FOOTWEAR, AND PROCESSES FOR MAKING ARTICLES OF FOOTWEAR OR COMPONENTS THEREOF NIKE INNOVATE CV (US) 2024-07-03 EP disclosed
US-20240200242-A1 KNIT TEXTILES AND UPPERS, AND PROCESSES FOR MAKING THE SAME NIKE, INC. 2024-06-20 US disclosed
US-11998080-B2 Textiles and articles and processes for making the same NIKE, INC. (US) 2024-06-04 US disclosed
EP-4060004-B1 COMPOSITE STRUCTURES INCLUDING A BONDING LAYER AND METHODS OF MAKING THE COMPOSITE STRUCTURE NIKE INNOVATE CV (US) 2024-05-29 EP disclosed
US-11987684-B2 Foam compositions and uses thereof NIKE, INC. (US) 2024-05-21 US disclosed
US-20240117136-A1 FOAM COMPOSITIONS AND USES THEREOF NIKE, INC. 2024-04-11 US disclosed
EP-4101964-B1 PROCESSES FOR MAKING ARTICLES COMPRISING A REFLOWED MATERIAL NIKE INNOVATE CV (US) 2024-04-10 EP disclosed
EP-3981281-B1 AN ARTICLE COMPRISING A REFLOWED MATERIAL AND A PRINTED ELEMENT, AND PROCESSES FOR MAKING THE SAME NIKE INNOVATE CV (US) 2024-03-27 EP disclosed
US-11939709-B2 Knit textiles and uppers, and processes for making the same NIKE, INC. (US) 2024-03-26 US disclosed
US-20230332339-A1 TEXTILES AND ARTICLES, AND PROCESSES FOR MAKING THE SAME NIKE, INC. 2023-10-19 US disclosed
US-20160058116-A1 ARTICLE OF FOOTWEAR WITH SOIL-SHEDDING PERFORMANCE NIKE, INC. 2016-03-03 US disclosed
US-20160058115-A1 ARTICLE OF FOOTWEAR WITH SOIL-SHEDDING PERFORMANCE NIKE, INC. 2016-03-03 US disclosed
US-20160058112-A1 ARTICLE OF FOOTWEAR WITH SOIL-SHEDDING PERFORMANCE NIKE, INC. 2016-03-03 US disclosed
US-20160058118-A1 ARTICLE OF FOOTWEAR WITH SOIL-SHEDDING PERFORMANCE NIKE, INC. 2016-03-03 US disclosed
US-20160058111-A1 ARTICLE OF FOOTWEAR WITH SOIL-SHEDDING PERFORMANCE NIKE, INC. 2016-03-03 US disclosed
US-20160058119-A1 ARTICLE OF FOOTWEAR WITH SOIL-SHEDDING PERFORMANCE NIKE, INC. 2016-03-03 US disclosed
US-20160058117-A1 ARTICLE OF FOOTWEAR WITH SOIL-SHEDDING PERFORMANCE NIKE, INC. 2016-03-03 US disclosed
US-20160058113-A1 ARTICLE OF FOOTWEAR WITH SOIL-SHEDDING PERFORMANCE NIKE, INC. 2016-03-03 US disclosed
US-20160058110-A1 ARTICLE OF FOOTWEAR WITH SOIL-SHEDDING PERFORMANCE NIKE, INC. 2016-03-03 US disclosed
US-20160058107-A1 ARTICLE OF FOOTWEAR WITH SOIL-SHEDDING PERFORMANCE NIKE, INC. 2016-03-03 US disclosed