Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS2R46 | P59540 | 12/20 | 0.61 |
| ▸ | TAS2R31 | P59538 | 2/20 | 0.46 |
| ▸ | TAS2R10 | Q9NYW0 | 2/20 | 0.46 |
| ▸ | RECQL | P46063 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | TERT | O14746 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10307313 | 1.00 | TAS2R46 (0.61) | TAS2R46TAS2R31TAS2R10RECQLMEN1 | |
| SCHEMBL27183429 | 0.91 | TAS2R46 (0.59) | TAS2R46TAS2R31TAS2R10RECQLMEN1 | |
| SCHEMBL27183431 | 0.91 | TAS2R46 (0.59) | TAS2R46TAS2R31TAS2R10RECQLMEN1 | |
| SCHEMBL27183427 | 0.91 | TAS2R46 (0.59) | TAS2R46TAS2R31TAS2R10RECQLMEN1 | |
| SCHEMBL30834897 | 0.80 | TAS2R46 (0.62) | TAS2R46TAS2R31TAS2R10RECQLMEN1 | |
| SCHEMBL10307305 | 0.80 | TAS2R46 (0.62) | TAS2R46TAS2R31TAS2R10RECQLMEN1 | |
| SCHEMBL1753395 | 0.80 | TAS2R46 (0.62) | TAS2R46TAS2R31TAS2R10RECQLMEN1 | |
| SCHEMBL18409983 | 0.77 | TAS2R46 (0.49) | TAS2R46TAS2R31TAS2R10RECQLMEN1 | |
| SCHEMBL30462356 | 0.76 | TAS2R46 (1.00) | TAS2R46TAS2R31TAS2R10RECQLMEN1 | |
| SCHEMBL15095950 | 0.75 | TAS2R46 (0.82) | TAS2R46TAS2R31TAS2R10RECQLMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8158372-B2 | Agonists of a bitter taste receptor and uses thereof | DEUTSCHES INSTITUT FÜR ERNÄHRUNGSFORSCHUNG POTSDAM-REHBRÜCKE (DE) | 2012-04-17 | — | — | US | disclosed |
| US-20100056621-A1 | AGONISTS OF A BITTER TASTE RECEPTOR AND USES THEREOF | DEUTSCHES INSTITUT FUR ERNAHRUNGSFORSCHUNG (DE) | 2010-03-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100056621-A1 | AGONISTS OF A BITTER TASTE RECEPTOR AND USES THEREOF | TAS2R4, TAS2R30, TAS2R40 | TAS2R46 25/4885TAS2R31 15/4885TAS2R10 6/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.