Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.42 |
| ▸ | POLQ | O75417 | 1/20 | 0.42 |
| ▸ | MLYCD | O95822 | 1/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12978337 | 0.88 | POLQ (0.43) | TRPV1POLQMLYCDNOTUMHTT | |
| SCHEMBL15472438 | 0.86 | TRPV1 (0.48) | TRPV1POLQNOTUMKMT2AMEN1 | |
| SCHEMBL12978274 | 0.86 | TRPV1 (0.40) | TRPV1POLQMLYCDNOTUMKMT2A | |
| SCHEMBL12978275 | 0.84 | TRPV1 (0.39) | TRPV1POLQMLYCDNOTUMMAPT | |
| SCHEMBL12978280 | 0.82 | TRPV1 (0.38) | TRPV1POLQMLYCDNOTUMMAPT | |
| SCHEMBL15474209 | 0.79 | MLYCD (0.40) | TRPV1POLQMLYCDNOTUMKMT2A | |
| SCHEMBL15472437 | 0.76 | KMT2A (0.43) | TRPV1POLQMLYCDNOTUMKMT2A | |
| SCHEMBL9902711 | 0.75 | NAMPT (0.45) | RAB9AL3MBTL1ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL16166157 | 0.73 | KMT2A (0.47) | TRPV1NOTUMKMT2AMEN1NPC1 | |
| SCHEMBL12978334 | 0.73 | POLQ (0.42) | TRPV1POLQMLYCDNOTUMKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9439427-B2 | Pesticidal pyrazole compounds | BASF SE (DE) | 2016-09-13 | — | — | US | disclosed |
| US-20160050927-A1 | Novel pesticidal pyrazole compounds | BASF SE (DE) | 2016-02-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160050927-A1 | Novel pesticidal pyrazole compounds | CYP51A1, PKM, NOTUM | TRPV1 931/4885POLQ 4344/4885MLYCD 306/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.