Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Maleic Anhydride. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Maleic Anhydride SCHEMBL28180718 | 0.93 | ALDH1A1 (0.34) | CA1CA9HSP90AA1ALDH1A1CYP2C9 | |
| Maleic Anhydride SCHEMBL27549538 | 0.90 | HSD17B10 (0.31) | HSP90AA1ALDH1A1CYP2C9HPGDALOX15 | |
| Maleic Anhydride SCHEMBL10920639 | 0.89 | — | — | |
| Maleic Anhydride SCHEMBL8745637 | 0.88 | FFAR3 (0.41) | HSP90AA1ALDH1A1CYP2C9HPGDALOX15 | |
| Maleic Anhydride SCHEMBL5638360 | 0.86 | ALOX15 (0.39) | CA1CA9HSP90AA1ALDH1A1CYP2C9 | |
| Maleic Anhydride SCHEMBL10482026 | 0.86 | ALDH1A1 (0.37) | CA1CA9HSP90AA1ALDH1A1CYP2C9 | |
| Maleic Anhydride SCHEMBL1761076 | 0.86 | ALDH1A1 (0.37) | CA1CA9HSP90AA1ALDH1A1CYP2C9 | |
| Maleic Anhydride SCHEMBL1332137 | 0.86 | — | — | |
| SCHEMBL10426127 | 0.86 | ALDH1A1 (0.37) | CA1CA9HSP90AA1ALDH1A1CYP2C9 | |
| Maleic Anhydride SCHEMBL191 | 0.86 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106456786-B | For controllably discharging the tablet of active principle | 科德宝两合公司 | 2019-10-11 | — | — | CN | disclosed |
| CN-109294200-A | A kind of preparation method of laminated silicate clay nano Composite polycarbonate material | 宁波高新区诠宝绶新材料科技有限公司 | 2019-02-01 | — | — | CN | disclosed |
| US-20180251597-A1 | COPOLYMER BASED ON DIMETHYL CARBONATE AND METHOD OF PREPARING THE SAME | NATIONAL CHENG KUNG UNIVERSITY (TW) | 2018-09-06 | — | — | US | disclosed |
| CN-106456786-A | Sheet-like structure for the controlled release of active substances | 科德宝两合公司 | 2017-02-22 | — | — | CN | disclosed |
| US-20160060391-A1 | COPOLYMER BASED ON DIMETHYL CARBONATE AND METHOD OF PREPARING THE SAME | NATIONAL CHENG KUNG UNIVERSITY (TW) | 2016-03-03 | — | — | US | disclosed |